The natural changes that occur to the skin over time, the pulling force of gravity downward, and volume loss are all contributors to the aging process of the face. Treatments for periorbital surgery can help relieve the symptoms associated with 3 different reasons. However, there needs to be more research detailing the safe use of CO2 lasers. Since there is currently no agreement on the optimal settings for a periorbital CO2 laser, this study aims to assess the safety of periorbital laser resurfacing when used in conjunction with lower blepharoplasty. All patients who had lower eyelid surgery performed between 2013 and 2018 by a single oculoplastic surgeon and received upper and lower eyelid fractionated CO2 laser resurfacing were analyzed retrospectively. About 59 patients were included. Six patients experienced side effects, including postinflammatory hyperpigmentation (3/59, 5.1%), prolonged superficial excoriations (1/59, 1.7%), prolonged hyperemia (1/59, 1.7%), and lower eyelid retraction requiring lower eyelid recession (1/59, 1.7%). After surgery, no one got sick. At their last post-operative appointment, 100% of patients reported feeling satisfied with the results. CO2 laser resurfacing is a safe and effective supplement to lower blepharoplasty, especially when used with aggressive settings
