Plant-based diets are associated with a reduced risk for prostate cancer (PC) progression and recurrence, according to a study presented at the 2023 ASCO Genitourinary Cancers Symposium. Vivian N. Liu and colleagues examined 2,038 men diagnosed with T1 to T3a PC who had completed a food frequency questionnaire a median of 31.5 months
after diagnosis. Overall and healthy plant-based dietary indices (PDI and hPDI, respectively) were calculated, and the associations with PC progression and recurrence were examined. A total of 204 progression events were identified during a median follow-up of 7.4 years; 169 were due to biochemical recurrence. Compared with men in the lowest quintile of PDI, those in the highest quintile had a significantly lower risk for PC progression and recurrence (HRs, 0.48 and 0.47, respectively). hPDI was not associated with PC progression or recurrence overall, but a significant reduction in the risk for recurrence was seen for men in the higher quintiles.
