The following observation was conducted to examine how REM sleep behavior disorder (RBD),  portrayed by anomalous rest practices of dream establishment, has been progressively perceived as a profoundly explicit marker of α‐synucleinopathies, and considered a non‐motor appearance and the most grounded marker of prodromal of Parkinson infection (PD).1, 2 RBD goes before clinically unmistakable neurodegenerative problems, with 73.5% changing over after 12‐year follow‐up. Late investigations have reliably indicated that higher convergences of urate, a powerful normal cancer prevention agent with neuroprotective properties,4, 5 are related with a lower danger of creating PD and with a more slow pace of PD progression.6-8 However, it stays obscure whether urate status is related with changed chances of having RBD. Hence we conclude that This is of importance in clinical and general wellbeing rehearses on the grounds that it could improve our comprehension of the likely part of urate in the pathogenesis of PD and help to build up an early stage avoidance technique against PD hazard.

Reference link- https://onlinelibrary.wiley.com/doi/10.1002/acn3.50929