The study was done to provide a description of the multimodal imaging findings of retinal lesions that clinically resemble retinal astrocytic hamartomas (RAHs), but also have unique characteristics that we believe represent a novel variant.

This study utilized the observational study method to obtain the related findings and data which are important to devise the conclusions regarding the unique characteristics that are believed to be representing a novel variant of the particular lesion. Five eyes in five patients with solitary retinal lesions evaluated at the retina division of three institutions. We describe the multimodal imaging findings including fundus photography, fundus autofluorescence, fluorescein angiography, spectral-domain optical coherence tomography (OCT), swept-source OCT, swept-source OCT angiography and ultrasonography.

The retinal lesions described shared similar appearance to RAHs but demonstrated unique features such as glistening granular appearance on fundus photographs with perivascular hyperreflectivity with OCT and OCT angiography.

The study concluded that the lesions described herein appear to have unique characteristics that warrant a designation as a novel RAH variant. The name presumed retinal pericapillary astrocytic hamartoma is suggested for that particular type.

Reference: https://bjo.bmj.com/content/early/2020/09/26/bjophthalmol-2020-317670