To identify significant precipitants of asthma and allergic illness, to emphasise the linkages between these triggers and immune system changes, and to evaluate innovative research on asthma prevention with an emphasis on atopic march. As asthma preventative techniques, allergen avoidance, allergen immunotherapy, IgE antagonists, respiratory infection prevention and treatment, and management of gastrointestinal and respiratory dysbiosis have all been investigated. Antenatal vitamin D supplementation in pregnant mothers, as well as intensive atopic dermatitis treatment to avoid the development of other allergic disorders, were thoroughly researched.
Asthma is a leading source of illness and lost productivity. Despite the enormous burden of this disease, the scientific community is still battling to identify an effective strategy of prevention. Although genetics cannot be changed, environmental changes and medication have been examined as modifiable risk factors. Many trials so far have been beneficial only for patients with certain traits. This is most likely due to the fact that asthma is a heterogeneous disorder with a wide range of triggers and clinical presentations. So far, a generally effective preventative technique has evaded us. However, if an intervention to prevent asthma and the allergic march can be developed, it will significantly enhance the quality of life for millions of patients while lowering healthcare costs.
