Deep vein thrombosis (DVT) and pulmonary embolism (PE) are both examples of venous thromboembolic occurrences (VTE). Despite advancements in prevention, detection, and therapy, VTE continues to be a major source of expense, disability, and mortality in postoperative and hospitalised patients (1, 2). VTE can cause chronic diseases such as postthrombotic syndrome (3), venous insufficiency, and pulmonary hypertension in addition to the acute symptoms of leg pain, edoema, and respiratory distress.

This Practice Bulletin has been updated to incorporate new research on the prevention of VTE in patients having gynecologic surgery, as well as the American College of Chest Physicians’ current surgical thromboprophylaxis recommendations (4). The scope of this text does not include a discussion of gynecologic surgery or chronic antithrombotic treatment.