The study’s goal was to measure parental quality of life (QoL), stress, and anxiety levels in parents of children with biliary atresia (BA), as well as variables related with parental QoL. This cross-sectional research included parents of children with BA. Validated questionnaires were utilized to measure parental QoL, stress, and anxiety levels. Using generalized linear mixed model analysis, researchers compared the results to reference data from the general population and identified related variables. The results are provided as a mean, standard deviation, or median. They had 61 parents with 39 children. Thirty-one youngsters had had a liver transplant (LTx). When compared to reference data, parents reported less family activities and greater emotional worry vs 92, but stronger family cohesiveness. The parental QoL, anxiety, and stress scores were comparable to the reference data. When compared to reference data, fathers and mothers performed better in the psychological area. There was no statistically significant difference in QoL between parents with children who had native livers and those who had undergone LTx. Physical QoL was negatively related with older age and a high anxiety characteristic in parents. Environmental QoL was negatively related with household income less than €35 000 per year and a strong anxiety characteristic.

QoL appears to be unchanged among parents of school-aged children with BA. Parents who have a high anxiety personality characteristic, are older, and have a low household income are more likely to have poor QoL.