Post-mastectomy radiotherapy (PMRT) to the chest wall and supraclavicular fossa is beneficial in breast cancer patients with four or more positive nodes, according to findings from the International Breast Cancer Study Group. The group also recommends that chest wall PMRT be considered in patients with one to three nodes who are aged 40 or younger and who have zero to seven uninvolved nodes or vascular invasion.

Abstract: Annals of Oncology, November 2012.