The study was done to investigate the accuracy of IOL power calculation formulas using SS-OCT.

410 patients and one eye from each patient were included in this study. Using optimized constants for SS-OCT biometry led to a significant decrease in median absolute error (MedAE) for Barrett, Haigis, and Hoffer Q formulas compared with using User Group for Laser Interference Biometry constants (P < .05).

Overall, Olsen (0.283 diopters [D]) and Kane (0.286 D) formulas had significantly lower MedAEs than RBF 2.0 (0.314 D), Haigis (0.322 D), SRK/T (0.371 D), Holladay 1 (0.376 D), and Hoffer Q (0.379 D) formulas under constant optimization (P < .05). The first four formulas with the lowest standard deviations of prediction error were Kane (0.451 D), Olsen (0.456 D), EVO 2.0 (0.460 D), and Barrett (0.470 D). Olsen (47.1%), Barrett (45.9%), Kane (45.4%), and EVO 2.0 (45.1%) formulas had greater proportions of eyes within ±0.25 D of the predicted refraction than Hoffer Q (35.9%), SRK/T (35.9%), and Holladay 1 (33.4%) formulas (P < .05).

The study concluded that optimization for SS-OCT biometry further improves the performance of formulas. The most accurate prediction of postoperative refraction can be achieved with Barrett, EVO 2.0, Kane, and Olsen formulas.

Reference: https://doi.org/10.3928/1081597X-20200514-02