Inflammatory bowel disease is now a global illness, with an increasing prevalence in the pediatric population. The purpose of this study is to determine the incidence and trend of IBD in a pediatric population aged 16 years in the Czech Republic’s South Moravian Region. Researchers analyzed data from 358 pediatric patients with newly diagnosed IBD at University Hospital Brno, a gastroenterology center for the entire pediatric population that treats all pediatric IBD patients in the South Moravian Region. The research included 3,488,907 youngsters over the course of 16 years. They identified 192 children as having Crohn’s disease (CD), 123 as having ulcerative colitis (UC), and 43 as having IBD-unclassified (IBD-U). The incidence of IBD rose from 3.8 per 100,000 people per year in 2002 to 14.7 per 100,000 people per year in 2017. The total incidence of IBD per 100,000 people per year was 9.8. CD 5.2, UC 3.4, and IBD-U 1.2 were the constituent occurrences per 100,000 people per year. In 2022, the incidence of IBD is expected to reach 18.9 per 100,000 people.

In the Czech Republic, the general prevalence of pediatric IBD, particularly CD, is growing, but trends in UC and IBD-U appear to be stable. These findings underscore the need of identifying risk factors in the growing frequency of IBD.