The aim of this study was to determine the characteristics and clinical outcomes of patients with the novel coronavirus (COVID-19) who presented with acute limb ischemia (ALI) at our institution. Whereas the pandemic is ongoing, early reports suggest the presence of a hypercoagulable state in COVID-19 patients that may be associated with increased thromboembolic complications and mortality.

This is a single-center retrospective review of patients presenting with ALI and an active diagnosis of COVID-19 pneumonia. The primary outcome was 30-day mortality. Secondary outcomes included successful revascularization and limb salvage. Successful revascularization was defined as absence of reocclusion of the target vessel at 30 days or death within 24 hours.

There were 2269 patients admitted with COVID-19 pneumonia from March 2020 to May 2020, and we identified 10 patients with ALI. Of these patients, the mean age was 62 ± 12 years, and peak D-dimer level during hospitalization was 5696 ± 4695 ng/mL. Common comorbidities included hypertension (100%), diabetes (60%), chronic kidney disease (40%), and coronary artery disease (20%). None of the 10 patients had previous peripheral revascularization.

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