Rosacea is an inflammatory dermatosis that mostly affects the cheeks, nose, chin, and forehead. Rosacea is distinguished by repeated flushing or transitory erythema, persistent erythema, phymatous changes, papules, pustules, and telangiectasia. It’s possible that the eyeballs are implicated as well. Rosacea has a significant negative influence on the quality of life, self-esteem, and well-being since it affects the face. In addition to general skincare, there are numerous authorised treatment options, both topical and systemic, for treating these characteristics. In some cases, strong pulse light, laser, and surgery are advantageous. Recent breakthroughs in the fundamental scientific study have highlighted the involvement of the innate and adaptive immune systems, as well as neurovascular dysregulation, in underpinning the rosacea range of clinical characteristics. In rosacea patients, both endogenous and external stressors can begin and exacerbate various pathways.
This study discusses the new pathophysiology-based phenotype-based diagnostic and categorization system, as well as new and developing treatment choices and methods. The study discusses novel topical and systemic formulations, as well as fresh research on therapy combinations. Furthermore, ongoing research on innovative treatment approaches will be described.
Reference: https://link.springer.com/article/10.1007/s40257-021-00595-7
