Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for September 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

CVS Halts Sales of OTC Zantac

MONDAY, Sept. 30, 2019 (HealthDay News) — CVS is the latest drugstore chain to stop selling over-the-counter Zantac (ranitidine), as well as the store’s own generic version of the heartburn medicine, because of contamination with a known carcinogen.

AP News Article

Rivaroxaban Cuts Recurrent Blood Clots in Obese Patients

MONDAY, Sept. 30, 2019 (HealthDay News) — Real-world evidence shows that rivaroxaban reduces the risk for recurrent venous thromboembolism (VTE) in morbidly obese patients, with similar safety and efficacy as warfarin, according to a study published in the October issue of Thrombosis Research.

Abstract/Full Text

Crude Incidence of Candidemia 8.7 Per 100,000 in 2012 to 2016

MONDAY, Sept. 30, 2019 (HealthDay News) — The crude incidence of candidemia was 8.7 per 100,000 population across four states in 2012 to 2016, according to a surveillance summary published in the Sept. 27 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Recommendations Updated for Management of Pediatric ADHD

MONDAY, Sept. 30, 2019 (HealthDay News) — In a clinical practice guideline from the American Academy of Pediatrics, published online Sept. 30 in Pediatrics, updated recommendations are presented for the evaluation and management of attention-deficit/hyperactivity disorder (ADHD) in children.

Clinical Practice Guideline
Perspective (subscription or payment may be required)

Heart Disease May Up Risk for Allopurinol-Linked Cutaneous AEs

MONDAY, Sept. 30, 2019 (HealthDay News) — Heart disease is associated with an increased risk for hospital admission for allopurinol-associated severe cutaneous adverse reactions, according to a study published online Sept. 25 in CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text

Eight Touchpoints May Predict Opioid Overdoses

FRIDAY, Sept. 27, 2019 (HealthDay News) — Eight candidate touchpoints are associated with increased risk of fatal opioid overdose, according to a study published in the Nov. 1 issue of Drug and Alcohol Dependence.

Abstract/Full Text (subscription or payment may be required)

DPP4 Inhibitors Do Not Up Risk of Inflammatory Bowel Disease

FRIDAY, Sept. 27, 2019 (HealthDay News) — Short-term use of a dipeptidyl peptidase 4 inhibitor (DPP4i) for the treatment of diabetes does not increase the risk of inflammatory bowel disease (IBD), according to a study published online Aug. 30 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Recommendations Developed for Evaluating Chronic Diarrhea

FRIDAY, Sept. 27, 2019 (HealthDay News) — In new American Gastroenterological Association (AGA) clinical practice guidelines, published in the September issue of Gastroenterology, recommendations are presented for laboratory evaluation of chronic watery diarrhea.

Abstract/Full Text

Infectious Disease Consultation May Lower Candida Mortality

FRIDAY, Sept. 27, 2019 (HealthDay News) — Mortality is lower for patients with candida bloodstream infection receiving an infectious disease consultation, according to a study published online Sept. 24 in The Lancet Infectious Diseases.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Average Annual Premium for Workers Increased in 2019

THURSDAY, Sept. 26, 2019 (HealthDay News) — In 2019, the average annual health insurance premium for workers increased slightly for single coverage and family coverage, according to a report published online Sept. 25 in Health Affairs.

Abstract/Full Text (subscription or payment may be required)

Many Systemic Lupus Erythematosus Patients Use Opioids

THURSDAY, Sept. 26, 2019 (HealthDay News) — Patients with systemic lupus erythematosus (SLE) are more likely to use opioids than persons without SLE, and most SLE patients who use opioids do so for more than one year, according to research published in the Sept. 27 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Telecontraception Seems a Promising Option for Patients

THURSDAY, Sept. 26, 2019 (HealthDay News) — Telecontraception — the provision of contraception through a website or smartphone app — is feasible and seems safe for patients, according to a research letter published in the Sept. 26 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Severe Adverse Cardiovascular Events Associated With Ibrutinib

THURSDAY, Sept. 26, 2019 (HealthDay News) — Cardiovascular adverse drug reactions (CV-ADR) occur in association with ibrutinib, according to a study published in the Oct. 1 issue of the Journal of the American College of Cardiology.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Vedolizumab Beats Adalimumab for Ulcerative Colitis Remissions

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — In moderate-to-severe ulcerative colitis, vedolizumab is superior to adalimumab for achieving clinical remission and endoscopic improvement, but not corticosteroid-free clinical remission, and ustekinumab is superior to placebo for inducing and maintaining remission, according to two studies published in the Sept. 26 issue of the New England Journal of Medicine.

Abstract/Full Text 1 (subscription or payment may be required)
Abstract/Full Text 2 (subscription or payment may be required)
Editorial (subscription or payment may be required)

Step-Up Strategy May Differ in Black Children With Asthma

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — In contrast to findings in black adolescents and adults, almost half of black children with poorly controlled asthma have a superior response to an increased dose of an inhaled glucocorticoid and almost half have a superior response to the addition of a long-acting beta-agonist (LABA), according to a study published in the Sept. 26 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

ACOG Updates Guidance on OTC Contraception Access

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — In a Committee Opinion published in the October issue of Obstetrics and Gynecology, the American College of Obstetricians and Gynecologists (ACOG) presents recommendations for expanding over-the-counter access to hormonal contraception.

Abstract/Full Text

ACA Provided Care to 1.9 Million People With Diabetes

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — The Affordable Care Act (ACA) provided care to an estimated 1.9 million people with diabetes, according to a research letter published online Sept. 23 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Teens Not Receiving Evidence-Based Treatment Options to Quit Smoking

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — Use of evidence-based treatment for nicotine use disorder (NUD) is extremely limited among adolescents and young adults with Medicaid coverage, according to a research letter published online Sept. 23 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Racial/Ethnic Disparities in Mortality Persist in the U.S.

WEDNESDAY, Sept. 25, 2019 (HealthDay News) — There are still racial and ethnic disparities in mortality, and these disparities are widening for some age groups, according to a study published online Sept. 24 in the American Journal of Preventive Medicine.

Abstract/Full Text

More Blood Pressure Drugs Recalled

TUESDAY, Sept. 24, 2019 (HealthDay News) — The recall of the commonly prescribed blood pressure drug losartan has been expanded once again to include an additional five lots.

More Information

For Seniors With T2DM, Insulin Use Up With Poor Health

TUESDAY, Sept. 24, 2019 (HealthDay News) — Among older individuals with type 2 diabetes, those with poor health have more prevalent insulin use, according to a study published online Sept. 23 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Protected Health Info Breaches Compromise Sensitive Data

MONDAY, Sept. 23, 2019 (HealthDay News) — Most protected health information (PHI) breaches compromise sensitive demographic and/or financial information, according to a research letter published online Sept. 23 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Emergency Departments Need to Up HIV Testing, Linkage to Care

MONDAY, Sept. 23, 2019 (HealthDay News) — HIV testing in South African emergency departments shows a high prevalence and incidence of HIV, as well as significant attrition along the HIV care cascade for HIV-positive individuals, according to a study published online Aug. 18 in EClinicalMedicine.

Abstract/Full Text

More Aggressive Tx Needed for Familial Hypercholesterolemia

MONDAY, Sept. 23, 2019 (HealthDay News) — Even with care in specialty clinics, low-density lipoprotein cholesterol (LDL-C) persists above target levels in more than half of patients with familial hypercholesterolemia (FH), according to a study published in the October issue of Atherosclerosis.

Abstract/Full Text

Racial/Ethnic Disparities Seen in PrEP Awareness, Discussions

FRIDAY, Sept. 20, 2019 (HealthDay News) — Considerable racial/ethnic disparities exist in HIV preexposure prophylaxis (PrEP) awareness, discussion, and use among men who have sex with men (MSM), according to research published in the Sept. 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Marijuana Use Common Among Adults With Medical Conditions

FRIDAY, Sept. 20, 2019 (HealthDay News) — Marijuana use is common among adults with medical conditions, especially younger people, according to a study published online Sept. 20 in JAMA Network Open.

Abstract/Full Text

Rate of Opioid Rx Increasing for Incisional Ocular Surgery

FRIDAY, Sept. 20, 2019 (HealthDay News) — The rate of filled opioid prescriptions is increasing for all types of incisional ocular surgery, according to a study published online Sept. 19 in JAMA Ophthalmology.

Abstract/Full Text (subscription or payment may be required)

Sertraline Does Not Reduce Depressive Symptoms by Week 6

FRIDAY, Sept. 20, 2019 (HealthDay News) — For patients with depression, sertraline does not reduce depressive symptoms at six weeks, but it does improve anxiety, mental health-related quality-of-life, and self-reported mental health, according to a study published online Sept. 19 in The Lancet Psychiatry.

Abstract/Full Text
Editorial

SGLT2 Inhibitors Linked to Lower Risk for Heart Failure

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — Use of sodium glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes is associated with a reduced risk for heart failure, but not a reduced risk for major cardiovascular events, compared with use of dipeptidyl peptidase 4 (DPP4) inhibitors, according to a study published online Aug. 29 in The BMJ.

Abstract/Full Text

Maker Halts Distribution of Generic Zantac Due to Possible Carcinogen

THURSDAY, Sept. 19, 2019 (HealthDay News) — Novartis, the maker of a generic form of Zantac, said Wednesday it will cease distribution of the medicine after investigations suggested that generic and branded versions contain a known carcinogen.

CBS News Article
More Information: FDA

House Speaker Unveils Plan to Lower Drug Costs

THURSDAY, Sept. 19, 2019 (HealthDay News) — House Speaker Nancy Pelosi has revealed a plan to lower the cost of medications for people on Medicare and those with private insurance.

AP News Article

ASTRO Issues Guideline for Radiation Tx in Pancreatic Cancer

THURSDAY, Sept. 19, 2019 (HealthDay News) — In a new American Society for Radiation Oncology clinical practice guideline, published in the September-October issue of Practical Radiation Oncology, recommendations are presented for radiation treatment of pancreatic cancer.

Abstract/Full Text

Seniors Should Undergo Annual Cognitive Health Assessment

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — Adults aged 65 years and older should undergo annual cognitive health assessments to improve recognition of mild cognitive impairment (MCI), according to a special article published online Sept. 18 in Neurology.

Abstract/Full Text (subscription or payment may be required)

Polypill Strategy Promising in Socioeconomically Vulnerable

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — In a socioeconomically vulnerable minority population, a combination pill (polypill) leads to greater reductions in systolic blood pressure and low-density lipoprotein (LDL) cholesterol levels, according to a study published in the Sept. 19 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Pharmacist in ED Cuts Time to Tx to Reverse Anticoagulation

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — Having a pharmacist in the emergency department significantly shortens the time to administration of treatment to reverse anticoagulation in patients with life-threatening bleeds or the need for urgent procedures, according to a study published online Aug. 22 in the Journal of Emergency Medicine.

Abstract/Full Text (subscription or payment may be required)

Many Older Patients With AML Not Receiving Active Treatment

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — Many older patients with acute myeloid leukemia (AML) do not receive any active treatment, and they have worse survival than those receiving active treatment, according to a study published online Sept. 4 in Cancer.

Abstract/Full Text (subscription or payment may be required)

Aortic, Mitral Regurgitation Risk Up With Fluoroquinolone Use

WEDNESDAY, Sept. 18, 2019 (HealthDay News) — The risk for aortic and mitral regurgitation is increased with current and recent fluoroquinolone (FQ) use, according to a study published in the Sept. 17 issue of the Journal of the American College of Cardiology.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Patients With Rheumatic Disease Often Have Trouble Accessing Care

TUESDAY, Sept. 17, 2019 (HealthDay News) — Americans with rheumatic disease struggle to access affordable specialty care, according to a national patient survey released by the American College of Rheumatology in conjunction with Rheumatic Disease Awareness Month.

2019 Rheumatic Disease Patient Survey

Men Less Knowledgeable About HPV, HPV Vaccination

TUESDAY, Sept. 17, 2019 (HealthDay News) — Men are less knowledgeable than women about human papillomavirus (HPV), HPV vaccination, and the correlation between HPV and cancer, according to a research letter published online Sept. 16 in JAMA Pediatrics.

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High-Risk Antibiotic Use Linked to Hospital-Associated C. Difficile

TUESDAY, Sept. 17, 2019 (HealthDay News) — Hospital-level high-risk antibiotic use is associated with the risk for hospital-associated (HA) Clostridioides difficile infection (CDI), according to a study published online Sept. 16 in Infection Control & Hospital Epidemiology.

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Initiating Empirical Tx for Sepsis Reduces Blood Culture Sensitivity

TUESDAY, Sept. 17, 2019 (HealthDay News) — When empirical antimicrobial therapy is initiated in patients with severe manifestations of sepsis, the sensitivity of blood cultures drawn shortly after treatment initiation is reduced, according to a study published online Sept. 17 in the Annals of Internal Medicine.

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Editorial (subscription or payment may be required)

Off-Label Ordering of Systemic Drugs Up for Children

TUESDAY, Sept. 17, 2019 (HealthDay News) — The rate of off-label ordering of systemic drugs has increased for children, according to a study published online Sept. 16 in Pediatrics.

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Editorial (subscription or payment may be required)

Combo Antithrombotic Therapy Increases Bleeding Risk

TUESDAY, Sept. 17, 2019 (HealthDay News) — Patients with chronic coronary artery disease or peripheral artery disease treated with the combination of rivaroxaban and aspirin face a greater risk for bleeding versus patients treated with aspirin alone, according to a study published in the Sept. 24 issue of the Journal of the American College of Cardiology.

Abstract/Full Text
Editorial (subscription or payment may be required)

Aspirin for Primary Prevention May Offer Net Benefit for Some

MONDAY, Sept. 16, 2019 (HealthDay News) — Aspirin for primary prevention of cardiovascular disease (CVD) is likely to result in net benefit for some patients, according to a study published online Sept. 17 in the Annals of Internal Medicine.

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Editorial (subscription or payment may be required)

Purdue Files for Bankruptcy Over Opioid Crisis Suits

MONDAY, Sept. 16, 2019 (HealthDay News) — OxyContin maker Purdue Pharma has filed for Chapter 11 bankruptcy, touching off what could be a fierce battle by dozens of states hoping to recoup billions spent fighting the opioid crisis.

The New York Times Article

Room for Improvement Found in HPV Vaccine Delivery Practices

MONDAY, Sept. 16, 2019 (HealthDay News) — There are areas for improvement for pediatricians and family physicians (FPs) in recommendation and delivery methods for the human papillomavirus (HPV) vaccine, according to a study published online Sept. 16 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Acetaminophen in Pregnancy May Affect Childhood Behavior

MONDAY, Sept. 16, 2019 (HealthDay News) — Acetaminophen use in mid-to-late pregnancy may have an adverse effect on early childhood neurocognitive outcome, according to a study published online Sept. 15 in Paediatric and Perinatal Epidemiology.

Abstract/Full Text

Donepezil Ups Risk for Hospital Admission for Rhabdomyolysis

MONDAY, Sept. 16, 2019 (HealthDay News) — Initiating donepezil to manage symptoms of Alzheimer disease or other dementias is associated with a higher risk for 30-day admission to the hospital with rhabdomyolysis compared with initiating rivastigmine or galantamine, according to a study published in the Sept. 16 issue of CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text

Delaying Treatment Worsens Head, Neck Cancer Outcomes

MONDAY, Sept. 16, 2019 (HealthDay News) — Delaying time to treatment initiation (TTI) beyond 60 days is associated with decreased overall survival and increased head and neck cancer recurrence, according to a study published online Sept. 12 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Continued Use Low Three Months After ED Opioid Rx for Acute Pain

MONDAY, Sept. 16, 2019 (HealthDay News) — Opioid use at three months after an emergency department visit where opioids were prescribed for acute pain is relatively low and not necessarily tied to opioid misuse, according to a study published in the August issue of Academic Emergency Medicine.

Abstract/Full Text

FDA to Assess First Drug Meant to Prevent Peanut Allergy

FRIDAY, Sept. 13, 2019 (HealthDay News) — A panel of experts at the U.S. Food and Drug Administration is set to weigh the pros and cons of what could be the first drug ever approved to prevent peanut allergy.

The Washington Post Article

FDA: Zantac May Contain Small Amounts of Known Carcinogen

FRIDAY, Sept. 13, 2019 (HealthDay News) — A substance that could cause cancer has been found in some ranitidine heartburn and ulcer medicines, including the brand-name drug Zantac, and the source of this contamination is being investigated, the U.S. Food and Drug Administration says.

More Information

Patient Factors May Predict Opioid Use After Discharge

FRIDAY, Sept. 13, 2019 (HealthDay News) — Certain factors may help clinicians identify which patients are more likely to have greater opioid use in the first month after major surgery, according to a study published online Aug. 5 in the Annals of Surgery.

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n-3 PUFAs Do Not Lower Risk for Early Preterm Delivery

THURSDAY, Sept. 12, 2019 (HealthDay News) — Supplementation with n-3 long-chain polyunsaturated fatty acids during pregnancy does not result in a lower incidence of early preterm delivery, according to a study published in the Sept. 12 issue of the New England Journal of Medicine.

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Screening for Opioid-Related Low Testosterone Underused

THURSDAY, Sept. 12, 2019 (HealthDay News) — More men with long-term opioid use are screened for low testosterone than men taking opioids for a short period of time; however, given the known link between opioid use and low testosterone, these rates were still lower than expected, according to a study published in the September issue of Mayo Clinic Proceedings: Innovations, Quality & Outcomes.

Abstract/Full Text

Allergy Immunotherapy May Decrease Asthma Progression

THURSDAY, Sept. 12, 2019 (HealthDay News) — Allergy immunotherapy (AIT) is associated with a decreased risk for asthma progression, particularly in younger patients, according to a study published online Aug. 13 in Allergy.

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EPA to Phase Out Chemical Testing on Mammals

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — The eventual elimination of chemical testing on mammals was announced Tuesday by the U.S. Environmental Protection Agency.

The New York Times Article
More Information: EPA

Risk for Long-Term Opioid Use Up in Hidradenitis Suppurativa

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — Patients with hidradenitis suppurativa (HS) have an increased risk for long-term opioid use, according to a study published online Sept. 11 in JAMA Dermatology.

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Purdue Pharma Tentatively Reaches Settlement in Opioid Lawsuits

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — OxyContin maker Purdue Pharma has reached a tentative settlement with a coalition of states and local governments that sued the company over its role in America’s ongoing opioid crisis, press reports say.

The New York Times Article
The Washington Post Article

Mycophenolate Mofetil Does Not Top MTX in Noninfectious Uveitis

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — For adults with noninfectious uveitis, mycophenolate mofetil is not associated with superior control of inflammation compared with methotrexate, according to a study published in the Sept. 10 issue of the Journal of the American Medical Association.

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Insulin Pump Therapy Use Has Increased Since 1995

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — Insulin pump usage has increased since 1995, especially among patients aged younger than 15 years, according to a study published online Sept. 5 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Full Chemo Doses May Improve Survival in Breast Cancer

WEDNESDAY, Sept. 11, 2019 (HealthDay News) — Maintaining full doses of chemotherapy, especially early in the treatment course, is important for survival of intermediate or high-risk breast cancer patients, according to a study published in the August issue of the Journal of the National Comprehensive Cancer Network.

Abstract/Full Text

Poverty Rate Drops, but Fewer Americans Have Health Insurance

TUESDAY, Sept. 10, 2019 (HealthDay News) — The percentage of Americans living in poverty declined in 2018, but the rate of those without health insurance increased, according to a U.S. Census Bureau report.

The New York Times Article
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Herd Protection Against Oral HPV Infections Seen Among Men

TUESDAY, Sept. 10, 2019 (HealthDay News) — In unvaccinated men aged 18 to 59 years, the prevalence of vaccine-type oral human papillomavirus (HPV) decreased between 2009 to 2010 and 2015 to 2016, according to a research letter published in the Sept. 10 issue of the Journal of the American Medical Association.

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California Passes Laws to Reduce Fake Medical Exemptions for Vaccines

TUESDAY, Sept. 10, 2019 (HealthDay News) — Bills to reduce fake medical exemptions for school children’s vaccinations were signed into law Monday by California Governor Gavin Newsom.

AP News Article

Age Modifies Effects of Estrogen Therapy in Women Without Ovaries

TUESDAY, Sept. 10, 2019 (HealthDay News) — For women aged 50 to 79 years, the effects of conjugated equine estrogens (CEE) do not differ according to bilateral salpingo-oophorectomy (BSO) status; however, age modifies the effect of CEE in women with prior BSO, according to a study published online Sept. 10 in the Annals of Internal Medicine.

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Quality-Improvement Tool Improves Iron Outcomes in Pregnancy

TUESDAY, Sept. 10, 2019 (HealthDay News) — A standardized iron deficiency (ID) toolkit increases detection and management of anemia during pregnancy, according to a study published Aug. 20 in PLOS Medicine.

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Opioid Maker Purdue Pharma Expected to File for Bankruptcy

MONDAY, Sept. 9, 2019 (HealthDay News) — Settlement talks with OxyContin maker Purdue Pharma over its role in the U.S. opioid crisis have reached a stalemate and the company is expected to file for bankruptcy, according to state attorneys general involved in the negotiations.

AP News Article

Sublingual Immunotherapy Safely Desensitizes Pediatric Peanut Allergies

MONDAY, Sept. 9, 2019 (HealthDay News) — Extended peanut sublingual immunotherapy (SLIT) demonstrates clinically significant desensitization in children with peanut allergies, according to a study published online Sept. 4 in the Journal of Allergy and Clinical Immunology.

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Use of Pain Reliever Tramadol May Up Risk for Hypoglycemia

MONDAY, Sept. 9, 2019 (HealthDay News) — Use of the widely prescribed opioid tramadol is associated with a greater risk for developing hypoglycemia compared with almost every other opioid, according to a study published online Aug. 28 in Scientific Reports.

Abstract/Full Text

Model Estimates Effect of Probiotics on Costs for Flu-Like Illnesses

MONDAY, Sept. 9, 2019 (HealthDay News) — Probiotics could reduce the health care and economic burden of flu-like respiratory tract infections (RTIs), according to a study published online Aug. 28 in Frontiers in Pharmacology.

Abstract/Full Text

White House Announces Nearly $2 Billion in Grants to Fight Opioid Epidemic

THURSDAY, Sept. 5, 2019 (HealthDay News) — Nearly $2 billion in grants to help fight the U.S. opioid epidemic will be handed out to states and local governments, the White House says.

AP News Article

Psychedelic Research Center Created at Johns Hopkins University

THURSDAY, Sept. 5, 2019 (HealthDay News) — A research center that will assess the use of psychedelic drugs to treat conditions such as addiction, alcoholism, and depression was announced by Johns Hopkins University.

ABC News Article

New Facebook, Instagram Pop-Ups Counter Vaccine Misinformation

THURSDAY, Sept. 5, 2019 (HealthDay News) — Educational pop-up windows will now appear on Facebook and Instagram when people search for vaccine-related content.

CNN Article

Position Statement Clarifies Benefits of Testosterone Therapy for Women

THURSDAY, Sept. 5, 2019 (HealthDay News) — Testosterone can be used for postmenopausal women with hypoactive sexual desire dysfunction (HSDD) but is not recommended for other symptoms or medical conditions, according to a position statement published online Sept. 2 in the Journal of Clinical Endocrinology & Metabolism.

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Underused Drug Combo May Up Survival in Lung Transplant

THURSDAY, Sept. 5, 2019 (HealthDay News) — A little used immunosuppression regimen may substantially improve survival following lung transplant, according to a study published online Aug. 28 in JAMA Network Open.

Abstract/Full Text

Algorithm Based on Response, Biology Guides Neuroblastoma Tx

THURSDAY, Sept. 5, 2019 (HealthDay News) — Use of a response- and biology-based treatment algorithm for intermediate-risk neuroblastoma is associated with excellent survival and reduces treatment for some patients, according to a study published online Aug. 6 in the Journal of Clinical Oncology.

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California Bill Targets Doctors Who Sell Fake Vaccine Medical Exemptions

WEDNESDAY, Sept. 4, 2019 (HealthDay News) — A bill that targets doctors who sell fraudulent medical exemptions for vaccinations was passed Tuesday by California’s state Assembly.

AP News Article

Cesarean Section Quality Initiative Cuts Opioid Use

WEDNESDAY, Sept. 4, 2019 (HealthDay News) — The enhanced recovery after surgery (ERAS) program, a quality improvement initiative that made changes to preoperative and postoperative processes, leads to reductions in opioid use without increased pain and with faster recovery, according to a study published in the September issue of Obstetrics & Gynecology.

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Proximity to Outbreak May Affect Attitudes in Vaccine Doubters

WEDNESDAY, Sept. 4, 2019 (HealthDay News) — Individuals with low trust in government health institutions who live close to recent measles outbreaks are likely to have more positive attitudes toward vaccination than those living farther away, according to a study published online Aug. 28 in PLOS ONE.

Abstract/Full Text

USPSTF Advises Meds to Reduce Risk for Primary Breast Cancer

TUESDAY, Sept. 3, 2019 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians offer risk-reducing medications to women at increased risk for breast cancer and at low risk for adverse medication effects. These recommendations form the basis of a final recommendation statement published in the Sept. 3 issue of the Journal of the American Medical Association.

Final Recommendation Statement
Evidence Report
Editorial 1 (subscription or payment may be required)
Editorial 2 (subscription or payment may be required)

Evidence Says Antipsychotics Do Not Prevent Delirium in Adults

TUESDAY, Sept. 3, 2019 (HealthDay News) — Current evidence does not support routine use of haloperidol or second-generation antipsychotics for prevention or treatment of delirium in hospitalized adults, according to two reviews published online Sept. 3 in the Annals of Internal Medicine.

Abstract/Full Text – Oh
Abstract/Full Text – Nikooie
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Adolescent Oral Contraceptive Use Tied to Later Depression Risk

TUESDAY, Sept. 3, 2019 (HealthDay News) — There is a long-term association between adolescent oral contraceptive (OC) use and depression risk in adulthood, according to a study published online Aug. 28 in the Journal of Child Psychology and Psychiatry.

Abstract/Full Text

Pediatric Flu Vaccine Guidelines Updated for 2019-20 Season

TUESDAY, Sept. 3, 2019 (HealthDay News) — In a policy statement published online Sept. 2 in Pediatrics, updated recommendations are presented regarding influenza vaccines for children, with no preference for any one product or formulation over another.

Abstract/Full Text

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