Female sex, Black race, Hispanic ethnicity, and younger age represent important determinants of health among adults with severe asthma, according to findings published in the Journal of Asthma. Njira Lucia Lugogo, MD, and colleagues examined clinical outcomes among patients with severe asthma in CHRONICLE according to common sociodemographic determinants of health. Among 1,884 patients enrolled between February 2018 and February 2020, most (69%) were female, White (75%), non-Hispanic (69%), and diagnosed with asthma as adults (60%). Female patients, Black and Hispanic patients, and younger patients had increased annualized rates of statistically significant exacerbations compared with male, White, non-Hispanic, and older patients, respectively. Additionally, Black, Hispanic, and younger patients had greater rates of asthma-related hospitalizations, and female and Black patients demonstrated worse symptom control and HRQOL. According to the researchers, awareness of these disparities among patients with severe asthma could increase quality of care for all patients.