For a study, researchers discussed the current research on skin microbiota. They gave an update on current knowledge of the role of bacteria in healthy skin as well as inflammatory and allergy skin illnesses. Computing advancements and high-throughput sequencing technologies have allowed for in-depth research of the microbiota composition and functioning of human skin. The majority of data produced so far was about the skin microbiome of healthy volunteers, but recent research has also looked at the dynamics of the microbiome in sick and wounded skin. The research was being published that assessed ways for manipulating the skin microbiota in order to modify illnesses and/or associated symptoms.

The microbiome of normal human skin was discovered to contain a significant degree of variety and interpersonal variation. The microbiota compositions of sick lesional skin (in atopic dermatitis and psoriasis) differed significantly from healthy skin. Microbial colonization has been shown to aid in the establishment of immune system homeostasis, whereas host-microbe interactions and genetically driven variation in stratum corneum characteristics may be connected to skin dysbiosis. Both are relevant for cutaneous illnesses characterized by abnormal immune responses and/or compromised skin barrier function. Modification of skin microbiota composition to restore host-microbiota equilibrium might be future disease-treatment or prevention techniques.