In children, solitary rectal ulcer syndrome (SRUS) is stated to be uncommon. Researchers examined the experience in a large cohort of children to look at clinical manifestations, endoscopic appearance, and treatment success. Between 2000 and 2018, clinical and endoscopic data were gathered. Children with SRUS identified by colonoscopy and confirmed by histology were included in the study. All children with SRUS were given behavioural therapy and a laxative in quantity. The majority of patients with ulcers received steroid enema, with some also receiving sulfasalazine or sucralfate enema. The median age of the 140 youngsters was 12 years, with 79 percent of them being males. The average duration of symptoms was 21 months. Rectal haemorrhage was reported in 131 cases, constipation in 38, and small, frequent stools in 79. The majority of the children had dyssynergic defecation symptoms such as extended sitting on the toilet, excessive straining, a sense of incomplete evacuation, and rectal digitation. Rectal prolapse was seen in 24 of the patients. In 101 cases, a rectal ulcer was discovered during a colonoscopy. Over the course of a 6-month median follow-up, 27 patients were lost to follow-up, and 71 of the remaining 113 cases exhibited clinical improvement.

The majority of SRUS patients appeared in their second decade with rectal haemorrhage and dyssynergic defecation. Three-fourths of the patients had ulcers. The medical treatment, which included behavioural modification and local therapy, yielded moderate results.