Takotsubo cardiomyopathy (TC) is related with a significant rate of morbidity and mortality in patients with aneurysmal subarachnoid haemorrhage (aSAH). Female patients with a low clinical grade are at the highest risk of getting TC, according to previous research. Intra-aortic balloon pumps (IABPs) have been shown to improve cardiac function in severe cases of TC and may be useful in the treatment of the condition. The authors looked back at the records of 1096 patients who had been admitted to their hospital with aSAH. A total of 405 patients were initially enrolled in the Barrow Ruptured Aneurysm Trial, with an additional 691 individuals evaluated from a later prospectively maintained aSAH database. According to the updated Ma, medical records were evaluated for the presence of TC.
In 26 patients with aSAH, TC was discovered. Female sex (OR 8.2, p = 0.005), Hunt and Hess grade > III (OR 7.6, p 0.001), aneurysm size > 7 mm (OR 3, p = 0.011), and clinical vasospasm (OR 2.9, p = 0.037) were found as risk variables for developing TC in the setting of aSAH in a stepwise multivariate logistic regression analysis. Female patients with big aneurysms, poor clinical grades, and clinical vasospasm are more likely to develop TC after aSAH. Even with an IABP in place, these patients have much greater rates of poor neurological outcomes. However, in some individuals with vasospasm, intensive intra-arterial endovascular therapy may improve the result.
Reference Link – https://thejns.org/view/journals/j-neurosurg/135/1/article-p38.xml