The purpose of the study was to look at the evidence for a link between acetaminophen (paracetamol) consumption and the development of rhinitis. The growing use of acetaminophen (paracetamol) as the preferred antipyretic throughout pregnancy and childhood was recommended as a risk factor for the development of asthma. Scarcity of well-designed birth cohort studies that look at paracetamol as a risk factor for the development of rhinitis. Many published studies have problems with confounding due to antibiotic usage, viral infections, and recollection bias. Prospective birth cohorts must devote sufficient time and research resources to effectively examine paracetamol exposure as a key variable of interest rather than as an accidental exposure variable obtained during normal questionnaire administration.

Reference:journals.lww.com/co-allergy/Abstract/2014/02000/The_association_between_acetaminophen_and_asthma_.6.aspx

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