The purpose of this article is to provide an overview of the key characteristics of anaphylaxis in the elderly, a subgroup of the population with specific clinical and physiological aspects that may impact the presentation and therapy of this entity. The frequency of allergic disorders in the elderly, including anaphylaxis, is growing as the population’s life expectancy rises. Older adults are more likely to die as a result of anaphylaxis, and certain comorbidities and pharmacological therapies they may be on may enhance that risk. 

Recognizing the key triggers, risk factors, and the vast range of presenting symptoms of anaphylaxis is therefore beneficial in its management, as is quick treatment start and comprehensive follow-up.