For a study, researchers sought to determine if a history of nocturnal enuresis influenced nightly urine frequency and to look into the causes of nocturia in adults.

The research comprised 143 individuals who experienced at least one incident of nocturia per night. The self-reported questionnaire gathered information on demographics, medical history, nocturnal enuresis in primary school, lower urinary tract symptoms, and frequency-volume charts.

About 52.4% of subjects had a history of nocturnal enuresis. Participants having a history of nocturnal enuresis in elementary school had considerably lower night-time urine frequency than those without such a history. A history of nocturnal enuresis was also found to be inversely linked with nighttime urine frequency on multivariate analysis (P<.01). Age and overnight urine frequency had a collinearity impact. The presence of nocturnal polyuria or hyperactive bladder in participants was unaffected by a history of nocturnal enuresis. On the other hand, participants with a history of nocturnal enuresis had fewer sleep disruptions (odds ratio 0.404).

Because of fewer sleep interruptions, a history of nocturnal enuresis may be adversely related to nighttime urine frequency. Furthermore, the development of nocturia may be affected by factors such as age and acquired disorders.