This study aimed to investigate the correlation between metabolic syndrome and CRS, with related risk factors for CRS according to data from the KNHANES.

The KNHANES surveyed individuals >19 years of age. CRS encompassed “symptom-based CRS” as defined by the European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Metabolic syndrome was diagnosed according to the American Heart Association/National Heart Lung and Blood Institute criteria. A χ2 analysis, univariate analysis, and multivariate analysis were conducted.

Twelve thousand fifteen individuals were analyzed in this study. CRS’s prevalence in patients with metabolic syndrome (high triglyceride level, reduced high-density lipoprotein level, and elevated blood pressure) was significantly higher than that in patients without metabolic syndrome. Allergic rhinitis was the only significant risk factor for CRS associated with metabolic syndrome.

The study concluded that CRS was more prevalent in patients with metabolic syndrome, especially those with allergic rhinitis, than in patients without metabolic syndrome. Accordingly, CRS should be considered in patients with metabolic syndrome and allergic rhinitis. Further studies are required to investigate the correlation between metabolic syndrome and CRS, with related risk factors for CRS.

Reference: https://journals.sagepub.com/doi/full/10.2500/ajra.2017.31.4445

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