Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis that frequently necessitates hospitalisation. The features and determinants of 30-day hospital readmissions in GPA were examined. Using the 2014 National Readmission Database, we conducted a cross-sectional study. Nonelective admissions with a main or secondary diagnosis of GPA were included. The study examined readmissions versus non readmissions in terms of attributes. Using mixed-effects multivariable logistic regression, independent predictors of readmissions were investigated. It examined a total of 9749 hospital admissions with GPA, with 2173 readmissions occurring within 30 days following release. The five major causes for readmissions were GPA, sepsis, pneumonia, severe respiratory failure, and acute renal damage. Readmissions for granulomatosis with polyangiitis were related with a longer period of stay and a lower rate of release home. Younger age, no private insurance, a higher Charlson Comorbidity Index, congestive heart failure, acute renal damage, and discharge to home health care were independent predictors of readmissions.

The study discovered a high rate of 30-day readmissions among GPA groups. Clinicians should be on the lookout for patients who are at high risk of readmission, such as those who are younger, have public insurance, have a greater comorbidity burden, have cardiac and renal problems, or have had a negative discharge disposition.