Maternal sepsis is a medical emergency that is a significant cause of maternal morbidity and death. Early detection of sepsis in a pregnant or postpartum patient might be difficult since the typical physiologic changes of pregnancy can obscure the signs and symptoms of sepsis. Bedside evaluation techniques may help detect maternal sepsis. In patients with suspected sepsis, timely and targeted antibiotic treatment, as well as fluid resuscitation, is crucial for survival. Once detected, a search for etiologies and the early implementation of source control measures will help to limit damages even further.  If the patient is in septic shock or is not responding to early therapy, multidisciplinary consultation and care escalation are required. Health care providers should be aware of the specific difficulties of sepsis in severely sick pregnant and postpartum patients, as well as preventive strategies. 

Adverse pregnancy outcomes may occur in conjunction with sepsis and should be predicted and avoided wherever feasible, or effectively handled when they do occur. Using a systematic strategy while treating a patient with suspected sepsis may minimize maternal morbidity and death.