The FDA has approved ingenol mebutate gel (Picato, LEO Pharma) for the topical treatment of actinic keratosis. At the 0.015% dose, the drug is indicated for once-daily use on the face and scalp for 3 days. At the 0.05% dose, it is indicated for once daily use on the trunk and extremities for 2 days.

Source: LEO Pharma.