Toxoplasmosis was an infectious disease caused by Toxoplasma gondii, an obligate intracellular parasite. For a study, researchers sought a link between T. gondii infection and aggression in autistic children. An analytical (comparative) cross-sectional study was used in the investigation. Between the ages of 3 and 12, 100 children (50 autistic and 50 normal) participated in the study. Age, socioeconomic level, and the absence of physical and mental illness were all considered. The blood sample test was conducted using the preschool aggressiveness scale and the enzyme-linked immunosorbent assay technique. To determine the existence of T. gondii infection, 5 milliliters of blood were taken. Autistic children had a greater rate of T. gondii infection than typical children. T. gondii-infected youngsters were also more aggressive than non-infected children. T. gondii infection was substantially greater in autistic children than in the control group. In addition, autistic children who had the parasite were more violent.