An intervention to reduce sedentary time and increase physical activity yields a transient improvement among patients with CKD, according to a study published in the Clinical Journal of the American Society of Nephrology. Researchers carried out the Sit Less, Interact, Move More intervention in a 24-week parallel-group, randomized trial among patients with CKD stages 2 to 5. Fifty-four participants in the intervention group underwent accelerometry at baseline and every 4 weeks to develop and monitor adherence to individualized plans targeting sedentary and stepping durations; 52 participants in the control group were given physical activity recommendations and underwent accelerometry at baseline and every 8 weeks. The study team observed no change in sedentary and stepping durations in the control group. The maximum decrease in sedentary duration (−43 minutes/ day) and number of steps/day (1,265) were observed in the intervention group at week 20. At week 24, these numbers were attenuated. Overall treatment effects between groups on sedentary and stepping durations and the number of steps/day were not significantly different in mixed-effect models. Significant reductions in secondary end points of BMI (−1.1 kg/m2) and body fat percentage (−2.1%) were seen in the intervention group.
