For a study, researchers quickly covered the classification techniques for Nonallergic Rhinitis (NAR), current understanding of its immunopathogenesis, scientific evidence-based therapy choices, and anecdotal clinical experience in selecting alternative treatment regimens for these difficult patients. NAR, also known as idiopathic rhinitis, irritant-induced rhinitis, and vasomotor rhinitis, is a heterogeneous syndrome that has been characterized in a variety of ways. However, due to its poorly understood mechanism(s), there was no consensus on a classification for this disorder. A typical patient was likely to have nasal congestion, postnasal discharge, and a cough, as well as sneezing, itching, and rhinorrhea to a lesser level. More detailed ways to classify rhinitis subtypes had been presented in recent publications. The disorder is thought to be caused by an autonomic imbalance resulting in an overactive parasympathetic nervous system and maybe an underactive sympathetic nervous system. The lack of knowledge of the mechanism(s) of action of NARs had slowed the development of new treatments for this illness.
To fully comprehend the neurogenic signaling mechanisms that contribute to this abnormal reaction, more research was needed. Until the researchers had specific therapy for NAR, they chose the medicine or combination of medications that are most suited to the patient’s symptomatic demands.
Reference:journals.lww.com/co-allergy/Abstract/2013/08000/Nonallergic_rhinitis__therapeutic_options.15.aspx
