Using nationally representative data, researchers examined trends in the past-month prevalence of cigarette smoking among persons with and without previous-year depression, substance use disorders (SUDs), or both. An exploratory, serial, cross-sectional study was conducted using data from 558,960 people aged 18 and up who took part in the 2006-2019 US National Surveys on Drug Use and Health. Self-reported cigarette smoking in the previous month, adjusted for sociodemographic factors. Of the 558,960 individuals polled, 41.4% (unweighted) were between the ages of 18 and 25, 29.8% (unweighted) were between the ages of 26 and 49, and 53.4% (unweighted) were female. 

From 2006 to 2019, the prevalence of past-month self-reported cigarette smoking decreased significantly among adults with MDE, dropping from 37.3% to 24.2% for an average annual percent change of −3.2 (95% CI, −3.5 to −2.8; P<.001), adults with SUD, dropping from 46.5% to 35.8% for an average annual percent change of −1.7 (95% CI, −2.8 to −0.6; P=.002), and adults with co-occurring MDE and SUD from 50.7% to 37.0% for an annual average annual percent change of −2.1 (95% CI, −3.1 to −1.2; P<.001). The prevalence of MDE and SUD decreased considerably with age, gender, and racial and ethnic grouping (all P<.05), with the exception of no significant decreases among American Indian or Alaska Native adults with MDE (P=.98) or SUD (P=.46). Differences in cigarette smoking prevalence between adults with and without MDE decreased significantly for adults overall, from 11.5% to 6.6%, for an average annual percent change of −3.4 (95% CI, −4.1 to −2.7; P<.001); significant average annual percent change declines were also seen for men (−5.1 [95% CI, −7.2 to −2.9]; P < .001); for women (−2.7 [95% CI, −3.9 to −1.5]; P<.001);  for those aged 18 through 25 years (−5.2 [95% CI, −7.6 to −2.8]; P<.001); for those aged 50 years or older (−4.7 [95% CI, −8.0 to −1.2]; P=.01); for Hispanic individuals (−4.4 [95% CI, −8.0 to −0.5]; P=.03), and for White individuals (−3.6 [95% CI, −4.5 to −2.7]; P<.001). For American Indian or Alaska Native people, prevalence did not change substantially between those with and without MDE from 2006 to 2012, but it was considerably greater for those with MDE from 2013 to 2019 (difference, 11.3%; 95% CI, 0.9 to 21.7; P=.04). Women’s differences between those with and without SUD decreased by an average yearly percent change of −1.8 (95% CI, −2.8 to −0.9; P=.001).

Between 2006 and 2019, there were substantial decreases in the incidence of self-reported cigarette smoking among US people with a major depressive episode, drug use disorder, or both, according to this exploratory, serial, cross-sectional investigation. However, further efforts were required to further lower the prevalence.

Reference:jamanetwork.com/journals/jama/article-abstract/2791406

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