The study aims to understand the clinical and incidence predictors for understanding the complications (critical) in patients who underwent endovascular therapy for treating PAD (peripheral artery disease). This study also includes institutional annual case volume.

The study included data from Japanese EVT (J-EVT) from 2012 to 2017. 92,224 cases were chosen to study the primary outcome measure for in-hospital critical complications, which led to urgent surgery or death in the hospital within thirty days from EVT. The researchers also took the institutional volume as a character during the multivariable logistic regression model study.

The critical complication incidence was 0.3%. The odds ratio for females was 1.75. Those who were above the age of 75 years had an odds ratio of 1.6. The patients with CLTI had an odds ratio of 2.12. Those who underwent regular dialysis had an odds ratio of 1.35. The nonambulatory status had a 1.66 odds ratio. The cerebrovascular disease, femoropopliteal TASC II, and infrapopliteal TASC D lesions had 1.76, 3.65, and 1.52 OR. The urgent revascularization had 5.10 OR. Moreover, the 4th quartile (more than 158 cases per year) had a significantly lower risk of complications. However, the 1st quartile had 0.13 OR.

After undergoing EVT for treating symptomatic PAD, 0.3% of subjects had critical complications, and high institutional volume had a positive association with a lower risk of complications.