For this study, researchers wanted to give the most recent research on the predictors of urinary tract infections (UTIs) and urosepsis after ureteroscopy (URS) for stone illness. Although reported rates of urosepsis were modest, research indicated that infectious complications account for about half of all post-URS problems. Antibiotic prophylaxis, preoperative UTI therapy, and a short procedure duration appeared to lower this risk. Patients with a higher Charlson comorbidity index, elderly patients, female gender, lengthy duration of pre-procedural indwelling ureteral stents, and patients with a neurogenic bladder and a high BMI were at increased risk.

Infectious complications following ureteroscopy might cause morbidity and even death. Although the majority of these were small, efforts must be made to reduce them, particularly in high-risk individuals. This involves using prophylactic antibiotics, reducing stent stay and procedure duration, identifying and treating UTI and urosepsis as soon as possible, and planning carefully in patients with a heavy stone burden and other comorbidities.