Colon manometry (CM) has developed as a technique for assessing children who have defecation issues. The purpose of this study was to see how useful CM was in directing treatment and predicting surgery in children with constipation. Retrospective analysis of children who had CM for four reasons: constipation, faecal incontinence, postsurgical assessment, and persistent intestinal pseudo-obstruction. Age, gender, follow-up, and CM characteristics such as gastrocolic response (GC) and the quality/quantity of high-amplitude propagating contractions were all variables (HAPCs). Medical, surgical, or no intervention interventions are available. Outcomes: reaction to CM-guided treatment modification, response to CM-guided first intervention (CMI), and CM prediction of surgery (CMS). The response to treatment was categorised based on the research indication. Five hundred fifty-five studies were included, with normal trials accounting for 24% of the total. A high response rate was related to a change in treatment guided by CM. The overall response to stimulant laxatives was 48% and was unrelated to CM results. Surgical procedures were more effective than medicinal or other treatments. Researchers observed no link between CM interpretation and CMI, however an aberrant CM predicted surgery. CMI and CMS were not related with GC or the presence/number of HAPCs. We also discovered no link between HAPC quality and CMI, however partially propagated HAPCs predicted surgery. However, prolonged follow-up and partially disseminated HAPCs were predictive of surgery in a logistic regression study.

Although CM is not indicative of effective medical intervention in paediatric defecation problems, an abnormal CM is prognostic of surgery. Only when medicinal treatments have failed and surgery is being considered should CM be performed.

Reference:https://journals.lww.com/jpgn/Fulltext/2020/02000/Utility_of_Colon_Manometry_in_Guiding_Therapy_and.19.aspx

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