The aim is To evaluate electrocardiogram markers to predict coronary involvement in patients with Kawasaki disease by assessing measures of ventricular repolarization parameters on the 12-lead electrocardiogram.

This cross-sectional study included 180 Spanish and Japanese patients ≤14 years of age with Kawasaki disease, with or without coronary involvement, from 2011 to 2016. We manually measured the Tp-Te/QT ratio and QTc interval (with Bazett’s formula) in 12-lead electrocardiogram in the acute and recovery period and explored their potential association with coronary involvement.

No association was found between Tp-Te/QT ratio obtained manually in V5 and V6 leads and coronary involvement in the acute. A QTc interval of <385 ms in lead V6 was associated with a 2.5-fold increased risk of coronary involvement (OR, 2.5; 95% CI, 1.2-5.3; P = .02). Manually measured QTc interval may be a marker of coronary disease in the acute period of Kawasaki disease.

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