In patients with metabolic syndrome, both all-cause and cardiovascular disease mortality appear to be substantially lowered in those with optimal 25-hydroxyvitamin D (25[OH]D) levels when compared with those with suboptimal levels, according to a study from European researchers. Future investigations should assess the role of vitamin D supplementation in optimizing 25(OH)D levels to reduce mortality in these individuals.

Abstract: Diabetes Care, May 2012.