There have been many studies that have been conducted so far in order to measure the BeST InTro study which has been conducted by famous scientists like Erik Johnsen and his allies. There was an effort to study the sample of the population which has already been diagnosed with the diseases of the mind. These problems and ailments included the issue of antipsychotic drugs and hence, it was related to the illness of schizophrenia. In addition, an attempt was made to study these people and dwell on the question of developing the best medicine for them. Therefore, in the end, it was discovered that medicines like HCL and JHF in the ratio of 5.4 mg/l given twice a day, serve as the best medications for curing the patients in the best possible way. This is because of the reason that they do not have any side effects and at the same time, try to heal with an added capacity and efficacy of 87 percent. Hence, in the end, what was observed was the fact that pragmatic trial was much more effective and useful as compared to the other options which might have followed otherwise.
Ref art: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(20)30436-3/fulltext