It was a Prospective 2-year factor-, cluster-, and reliability-multicenter analysis. The objective for a study was to demonstrate the uniqueness and utility of potentially valuable functional outcomes. There are many functional outcomes that can be included as variables in low back pain (LBP) research. Participants with and without current LBP (n=1049) were included. About 42 different functional outcomes were examined at 7 visits (baseline, 4 weeks, 3 months, 6 months, 9 months, 1 year, and 2 years). Two exploratory factor analyses were performed (for baseline values and changes scores to 3 months post-baseline) (maximum likelihood extraction, varimax factor rotation). The most robust factor-loading results were chosen for the hierarchical cluster analyses that followed (average linkage, Euclidean distance measure). Reliability analyses were then calculated for each cluster, time point, and result using intraclass correlation coefficients, standard error of measurements, and coefficients of variation. The cross-sectional values factor analysis found nine factors with a cumulative variance explanation of 61.7% and 13 distinct ones. Around seven of the outcomes were unique, according to the change-score factor analysis, which identified nine factors with a total variance explanation of 61.8%. For both cross-sectional and change-score profiles, 10 outcomes were most relevant, 11 for cross-sectional, and 4 for change scores. Patients with pain levels ranging from 1 to 3 have similar patterns (cluster 2). Grades 0 (cluster 1) and 4 (cluster 3) are distinct from other steps and cannot be combined. The majority of biomechanical outcomes were quite dependable and had minor measurement errors. In the context of objective functional assessments (such as trunk range of motion, dynamic and static balance, strength, and muscle fatigue resistance) and body features, the researchers discovered 25 potentially significant functional outcomes. Beyond the known core set of products, the methodology may aid in the selection of relevant functional results and rate effects.