The goal of this study is to conduct a review on work-associated irritable larynx syndrome (WILS), a hyperkinetic laryngeal condition caused by occupational irritant exposure. Clinical signs include dysphonia, cough, dyspnoea, and globus pharyngeus. WILS is a clinical diagnosis that might be difficult to distinguish from asthma. WILS treatment options include medicinal and behavioural therapy. Laryngeal-centred upper airway symptoms caused by airborne irritants have been described in this study under a number of diagnostic names, including WILS, vocal cord dysfunction (VCD), laryngeal hypersensitivity, and laryngeal neuropathy, among others. The underlying pathophysiology is yet unknown; nevertheless, the clinical picture implies that the illness is complex. According to newer research, central neural plasticity, inflammatory processes, and psychological variables are all potential causes.

WILS might be caused by central neural network plasticity following noxious exposure and/or viral infection, inflammation, and intrinsic patient variables such as psychological status. Treatment is tailored to the person and usually includes one or more of the following: workplace environmental modifications, GERD treatment, behavioural/speech therapy, psychotherapy counselling, and neural modifiers.

Reference:https://journals.lww.com/co-allergy/Abstract/2015/04000/Work_associated_irritable_larynx_syndrome.8.aspx