The American Academy of Dermatology (AAD) launched DataDerm™ in 2016 as the clinical data registry platform of AAD. DataDerm is approved by Centers for Medicare & Medicaid Services (CMS) as a Qualified Clinical Data Registry (QCDR) for the Merit-Based Incentive Payment System (MIPS). The ultimate purpose of DataDerm is to provide dermatologists with a registry and database that will serve as a vehicle to advance the specialty in the domains of science, discovery, education, quality assessment, quality improvement, advocacy, and practice management. DataDerm is currently the largest clinical registry and database of patients receiving dermatological care in the world. As of December 31, 2019, DataDerm contained data from 10,618,879 unique patients and 32,309,389 unique patient visits. Depending on the reporting period, 800-900 practices (representing 2,400-2,600 clinicians) actively participate in DataDerm by submitting data. This manuscript provides the first of a planned series of annual updates of the status of DataDerm. The purpose of this article is to present the rationale for the creation, maintenance, history, and current status of DataDerm, as well as the future plans for DataDerm.Copyright © 2020. Published by Elsevier Inc.