To assess the effect of the EVO+ (V5) Visian implantable collamer lens implantation on mesopic visual performance, quality of vision (QoV) and quality of life (QoL).
Prospective interventional case series.
Thirty-six eyes of 36 participants who underwent EVO+ implantation for myopia were evaluated preoperatively and at postoperative visits 1 week, and 1, 3 and 6 months. Visual acuity (VA), mesopic contrast sensitivity (CS) with and without halogen and xenon-type glare sources were evaluated at each visit. Subjective QoV was assessed with the QoV questionnaire and QoL assessed with the QIRC questionnaire at each visit. Ring-shaped dysphotopsia was also assessed at each postoperative visit. Linear, cumulative link and logit mixed models were fitted to analyze the effect of the EVO+.
Following EVO+ implantation, VA significantly (P≤.012) improved at the four postoperative visits. Mesopic CS progressively improved at 1-, 3- and 6-months postoperatively (P≤.012). Halogen glare CS decreased at 1 week and halogen and xenon glare CS improved at 6 months (P≤.016). Photostress recovery time after halogen glare improved at 3 and 6 months (P≤.004). QoV scores improved at 1 week, and 3 and 6 months (P≤.001). QIRC scores improved postoperatively (P<.001). Ring-shaped dysphotopsia decreased at 3 and 6 months (P≤.007).
EVO+ implantation provides good mesopic visual performance, QoV and QoL during up to 6 months follow-up. Some activities performed under mesopic conditions with glare sources may be affected during the first postoperative week. Ring-shaped dysphotopsia is negligibly bothersome 6 months after surgery.

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