An urgent need to define clinical and laboratory parameters to predict progression to the severe and lethal forms of Coronavirus Disease 2019 (COVID 19). To investigate the direct/total bilirubin ratio (D/TBil), as a novel parameter, to predict the poor survival of COVID-19 Pneumonia.
The clinical characteristics and laboratory parameters of hospitalized COVID-19 pneumonia patients were analyzed from 20 March to 1 August 2020, in a tertiary hospital, retrospectively. All remarkable variables were selected for a forward stepwise binary logistic regression analysis to define the independent risk factors for mortality.
Among 537 (248 women and 289 men) patients were separated into two groups for analysis; survivors vs deceased’s. The mean age of the deceased group was statistically significantly higher than the survivor group 72 (30-92) years vs 50 (18-97) years, (p 0.5, and 2.4 times in patients with NLR > 4.
D/TBil > 0.5 was associated with as a novel parameter to poor survival of COVID-19 on admission. Also, the combination of age, gender, the presence of hypertension, D/TBil, and NLR contributed significantly to predicting the poor survival of COVID-19.

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