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Infection

Knee Arthrodesis Using a Compression Clamp and a Single-Plane External Fixator to Treat Infection.

May 23, 2022

In patients with knee infection, arthrodesis by external fixation is a limb-salvage procedure appropriate in highly selected patients. No hardware that might lead to infection is left in situ. However...

Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach.

May 16, 2022

We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of ...

Rescue venovenous extracorporeal membrane oxygenation for the deterioration of acute respiratory distress syndrome in pediatric liver transplantation.

May 16, 2022

Twenty percent of pediatric patients with BA develop ACLF with increased mortality while awaiting LT. Respiratory complications are common in pediatric ACLF and are associated with increased morbidity...

Association of immediate reinsertion of new catheters with subsequent mortality among patients with suspected catheter infection: a cohort study.

May 09, 2022

Central venous catheter (CVC) insertion complications are a prevalent and important problem in the intensive care unit (ICU), and source control by immediate catheter removal is considered urgent in p...

Upper Extremity Infections in the Transplant Population.

May 09, 2022

As the duration of lifetime survival after organ transplantation continues to increase, the consequences of long-term immunosuppression, such as opportunistic and rare infections, are a high-risk real...

#VisualAbstract: Fewer hospital admissions and death were seen with SARS-CoV-2 Delta (B.1.617.2) compared to Omicron (B.1.1.529) variant infections

Apr 28, 2022

1. The risk of hospitalization and death was lower among cases infected with Omicron variant compared to Delta. 2. In unvaccinated cases, prior COVID-19 infection provided moderate protection. ...

Methylsulfonylmethane protects against lethal dose MRSA-induced sepsis through promoting M2 macrophage polarization.

Apr 25, 2022

Multi-drug-resistant bacterial infections, which have become a global threat, lack effective treatments. The discoveries of non-antibiotics with different modes of antibacterial action, such as methyl...

A Yersiniabactin-Producing Klebsiella aerogenes Strain Causing an Outbreak in an Austrian Neonatal Intensive Care Unit.

Apr 18, 2022

Yersiniabactin, a siderophore with a high affinity to iron, has been described as a potential virulence factor in Enterobacteriaceae. Klebsiella aerogenes is a gram-negative rod known to cause invasiv...

Prognostic accuracy of using lactate in addition to the quick Sequential Organ Failure Assessment score and the National Early Warning Score for emergencydepartment patients with suspected infection.

Apr 11, 2022

The aim of this study was to determine whether: (1) the quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) and National Early Warning Score (NEWS) clinical prediction tools alone, (2) ...

Presepsin production in monocyte/macrophage-mediated phagocytosis of neutrophil extracellular traps.

Apr 11, 2022

Presepsin, a biomarker discovered in Japan, has been clinically applied as a diagnostic aid for sepsis. Recently, however, it has been reported that presepsin levels are elevated in patients with seve...

Percutaneous Endoscopic Gastrostomy Tube Timing in Head and Neck Cancer Surgery.

Apr 04, 2022

To examine outcomes and complications in patients receiving a percutaneous endoscopic gastrostomy (PEG) tube on the same day of head and neck cancer (HNC) surgery versus later in hospitalization.The 2...

Risk factors for septic arthritis and multiple arthroscopic washouts: minimum 2-year follow-up at a major trauma centre.

Apr 04, 2022

Septic arthritis (SA) is a dangerous condition that requires emergency treatment. Managed by culture-specific antibiotics, irrigation, and debridement (I&D), some patients require repeat surgical ...

Allogeneic blood transfusions and infection risk in lumbar spine surgery: An American College of Surgeons National Surgery Quality Improvement Program Study.

Mar 28, 2022

Allogenic blood transfusions can lead to immunomodulation. Our purpose was to investigate whether perioperative transfusions were associated with postoperative infections and any other adverse events ...

Retrospective Identification of Infection in the Emergency Department: A Significant Challenge in Sepsis Clinical Trials.

Mar 21, 2022

This study examined three methods for retrospectively identifying infection in emergency department (ED) patients: modified objective definitions of infection (MODI) from the CDC/NHSN, physician adjud...

A Clinical Diagnostic Study: Fibulin-2 is a Novel Promising Biomarker for Predicting Infection.

Mar 21, 2022

Infection remains a major cause of morbidity and mortality in hospital. As uncontrolled early infection may develop into systemic infection and eventually progress to sepsis, it is important to addres...

Transcriptional switch of hepatocytes initiates macrophage recruitment and T cell suppression in endotoxemia.

Mar 14, 2022

The liver plays crucial roles in the regulation of immune defense during acute systemic infections. However, the roles of liver cellular clusters and intercellular communication in the progression of ...

Outcome and Predictors of Septic Failure following Total Joint Arthroplasty for Prior Septic Arthritis of Hip and Knee joint.

Mar 14, 2022

Arthroplasty patients with prior septic arthritis are at high risk of developing periprosthetic joint infection (PJI). The aims of this study are to investigate the outcome and predictors of septic fa...

[Glucose, Lactate, NGAL and Coefficient of Energy Balance in Synovial Fluid in Patients with Hip and Knee Prosthetic Joint Infection].

Mar 07, 2022

PURPOSE OF THE STUDY Laboratory methods are central to prosthetic joint infection (PJI) diagnosis. Most research teams focus on detection of specific inflammatory markers, causative pathogens, or on a...

Impact Of The Ileal Microbiota On Surgical Site Infections In Crohn's Disease: A Nationwide Prospective Cohort.

Feb 28, 2022

Surgery is performed in 50-70% of Crohn's disease (CD) patients, and its main risk is surgical site infection (SSI). The microbiota has been extensively assessed in CD but not as a potential risk fact...

The role of serum D-Dimer for the diagnosis of periprosthetic shoulder infection.

Feb 21, 2022

D-Dimer was recently identified as an additional biomarker in the diagnosis of hip and knee periprosthetic joint infection (PJI). Currently, there is only one study in literature dealing with the role...