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Vaccines

A prolonged, nationwide measles outbreak despite very high vaccination coverage in Israel, 2018-19.

Oct 11, 2021

. A major, prolonged measles outbreak occurred in Israel during 2018-19, despite vaccination coverage rates of 97% and 96% for the first and second doses, respectively, of measles containing vaccine (...

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002).

Sep 06, 2021

COVID-19 vaccine supply shortages are causing concerns about compromised immunity in some countries as the interval between the first and second dose becomes longer. Conversely, countries with no supp...

Vaginal Delivery of Vaccines.

Sep 06, 2021

Recent estimates suggest that one in two sexually active individuals will acquire a sexually transmitted infection by age 25, an alarming statistic that amounts to over 1 million new infections per da...

Factors associated with COVID-19 vaccination intentions and attitudes in France.

Sep 06, 2021

The objective of the study is to investigate the factors associated with COVID-19 vaccination intentions and attitudes in France.An online cross-sectional study was conducted among a representative sa...

The Effectiveness of Inactivated SARS-CoV-2 Vaccine (CoronaVac) on Antibody Response in Participants Aged 65 Years and Older.

Aug 26, 2021

In this study, it was aimed to determine the antibody responses after the two doses of inactivated SARS-CoV-2 vaccinations in people who is above 65-years old, and to evaluate the factors affecting th...

A phase III randomized, open-label, non-inferiority clinical trial comparing liquid and lyophilized formulations of oral live attenuated human rotavirus vaccine (HRV) in Indian infants.

Aug 26, 2021

The human rotavirus vaccine (HRV; , GSK) is available as liquid (Liq) and lyophilized (Lyo) formulations, but only Lyo HRV is licensed in India. In this phase III, randomized, open-label trial (NCT021...

Introduction of novel putative immunogenic targets against Proteus mirabilis using a reverse vaccinology approach.

Aug 26, 2021

Multi-drug resistance of Proteus mirabilis, a frequent cause of catheter-associated urinary tract infections, renders ineffective treatment. Therefore, new advanced strategies are needed to overcome i...

Assessment of humoral and cellular immunity induced by the BNT162b2 SARS-CoV-2 vaccine in healthcare workers, elderly people, and immunosuppressed patients with autoimmune disease.

Aug 23, 2021

The development of vaccines to prevent SARS-CoV-2 infection has mainly relied on the induction of neutralizing antibodies (nAbs) to the Spike protein of SARS-CoV-2, but there is growing evidence that ...

Implementation of a Coronavirus Disease 2019 Vaccination Condition of Employment in a Community Nursing Home.

Aug 23, 2021

The rate of coronavirus disease 2019 (COVID-19) vaccination uptake by US nursing home staff remains low despite the increased risks of viral transmission and related morbidity and mortality in this se...

COVID-19 Vaccine Hesitancy Among Patients in Two Urban Emergency Departments.

Aug 19, 2021

Widespread vaccination is an essential component of the public health response to the COVID-19 pandemic, yet vaccine hesitancy remains pervasive. This prospective survey investigation aimed to measure...

CME/CE: COVID-19-Related Medical Mistrust Can Impact Inequities among Black People With HIV

Aug 16, 2021

This course discusses a study that examined a convenience sample of Black Americans who are HIV-positive or associations of COVID-19-related medical mistrust with vaccine and treatment hesitancy in Ma...

B and T cell response to SARS-CoV-2 vaccination in health care professionals with and without previous COVID-19.

Aug 16, 2021

In recent months numerous health care professional acquired COVID-19 at the workplace resulting in significant shortages in medical and nursing staff. We investigated how prior COVID-19 affects SARS-C...

Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2.

Aug 16, 2021

Recent reports demonstrate robust serological responses to a single dose of messenger RNA (mRNA) vaccines in individuals previously infected with SARS-CoV-2. Data on immune responses following a singl...

Cellular and humoral immunogenicity of a SARS-CoV-2 mRNA vaccine in patients on haemodialysis.

Aug 16, 2021

Patients with chronic renal insufficiency on maintenance haemodialysis face an increased risk of COVID-19 induced mortality and impaired vaccine responses. To date, only a few studies have addressed S...

Modeling the population effects of escape mutations in SARS-CoV-2 to guide vaccination strategies.

Aug 12, 2021

SARS-Cov-2 escape mutations (EM) have been detected and are spreading. Vaccines may need adjustment to respond to these or future mutations. We designed a population level model integrating both wanin...

Patient-reported safety and tolerability of the COVID-19 vaccines in persons with rare neuroimmunological diseases.

Aug 12, 2021

The COVID-19 vaccines are currently recommended for people with rare neuroimmunological diseases such as neuromyelitis optica spectrum disorder (NMOSD), MOG-antibody disease (MOGAD), and transverse my...

COVID-19 vaccine safety and efficacy in patients with Immune-Mediated Inflammatory Disease: Review of available evidence.

Aug 09, 2021

Dermatologists diagnose and treat many immune-mediated inflammatory diseases (IMID). Understanding the inherent immune dysregulation of these diseases as well as the additional disruption that comes a...

Evaluation of the dose-effect association between the number of doses and duration since the last dose of COVID-19 vaccine, and its efficacy in preventing the disease and reducing disease severity: A single centre, cross-sectional analytical study from India.

Aug 09, 2021

To evaluate the dose-effect association between COVID-19 vaccination and probability of turning RT-PCR positive and to assess the correlation between disease severity and vaccination status.A single c...

Immune response of adult horses, pregnant mares and foals to an experimental vaccine with recombinant EMA-2 protein of Theileria equi.

Aug 05, 2021

Equine theileriosis, caused by the Theileria equi protozoan, is a disease of worldwide importance. T. equi expresses surface proteins, of which the EMA-2 protein is a promising antigen for vaccine use...

Oral vaccination with attenuated Salmonella encoding the Trichinella spiralis 43-kDa protein elicits protective immunity in BALB/c mice.

Aug 02, 2021

A vaccine against Trichinella spiralis infection is urgently needed to interrupt its transmission from domestic animals to humans. However, no vaccine against T. spiralis is currently available. Our p...