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Anemia Nephrology

Anemia in pregnant women according to two different assessment criteria (who versus CDC).

May 23, 2022

To determine the prevalence of anemia among pregnant women and the associated factors and perinatal outcomes according to two different diagnostic criteria: the World Health Organization (WHO) and the...

Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis.

May 16, 2022

The spleen plays a key role in iron homeostasis. It is the largest filter of the blood and performs iron reuptake from old or damaged erythrocytes. Despite this role, spleen iron concentration has not...

Intravenous iron sucrose is safe but does not prevent development of anemia or iron deficiency in healthy cats undergoing serial venipuncture.

May 09, 2022

To evaluate IV iron sucrose safety and impact on hematologic and iron indices in healthy cats.5 healthy research cats.Cats were administered iron sucrose (0.5 mg/kg, IV) over 30 minutes. Monitoring fo...

High risk of adverse birth outcomes among adolescents living with HIV in Botswana compared to adult women living with HIV and adolescents without HIV.

May 02, 2022

Adolescent girls are three times more likely to be living with HIV than boys of the same age. Prior studies have found associations between adolescent pregnancies and increased maternal morbidity and ...

Epidemiology and outcomes in patients with anemia of CKD not on dialysis from a large US healthcare system database: a retrospective observational study.

May 02, 2022

Optimal management of anemia of chronic kidney disease (CKD) remains controversial. This retrospective study aimed to describe the epidemiology and selected clinical outcomes of anemia in patients wit...

Downregulation of SATB1 by miRNAs Reduces Megakaryocyte/Erythroid Progenitor Expansion in pre-clinical models of Diamond Blackfan Anemia.

Apr 25, 2022

Diamond Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome that is associated with anemia, congenital anomalies, and cancer predisposition. It is categorized as a ribosomopathy, becaus...

Treatment patterns and burden of myelosuppression for patients with small cell lung cancer: A SEER-medicare study.

Apr 18, 2022

To depict the treatment journey for patients with small cell lung cancer (SCLC) and evaluate health care resource utilization (HCRU) associated with myelosuppression, a complication induced by chemoth...

A Survey of Burnout Among Nephrologists in the United States

Apr 12, 2022

Burnout reduces job satisfaction and results in poor patient outcomes, yet it was still understudied in the field of nephrology. Burnout was studied in a group of nephrologists to see how often it was...

Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable engraftment by repeated donor lymphocyte infusions for a Chinese patient with transfusion-dependent hemoglobin (Hb) Hammersmith and massive splenomegaly.

Apr 11, 2022

Hemoglobin (Hb) Hammersmith is a rare form of unstable β-chain hemoglobinopathy causing hemolytic anemia. This rare event led to a more serious transfusion-dependent phenotype in a patient. It was su...

Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model.

Apr 04, 2022

Polymerization of deoxygenated sickle hemoglobin (HbS) leads to erythrocyte sickling. Enhancing activity of the erythrocyte glycolytic pathway has anti-sickling potential as this reduces 2,3-diphospho...

Anaemia among Pregnant Women: Prevalence and Pattern at Booking Clinic of a Tertiary Health Care Facility in North Central Nigeria.

Apr 04, 2022

Anaemia in pregnancy is an important reproductive health problem associated with increased maternal and perinatal morbidity and mortality. Despite the use of iron and folate supplementation, anti-helm...

Molecular detection and genetic analysis of porcine hemoplasmas in commercial pig farms from Thailand reveal a putative novel species.

Mar 28, 2022

Hemoplasma is a trivial name for hemotropic Mycoplasma spp., which can attach to the surface of red blood cells leading to deformity and anemia in a wide range of mammalian animals, including pigs. In...

Route of postpartum oxytocin administration and maternal hemoglobin decline - A randomized controlled trial.

Mar 21, 2022

Oxytocin uterotonic agents are routinely administered during the third stage of labor, however, the administration route is varying, intravenously or intramuscularly. We aimed to compare the effect of...

Cerebral Infarction due to Severe ADAMTS-13 Deficiency with Normal Hematological Parameters: A Potentially Cause of Cryptogenic Stroke.

Mar 21, 2022

Thrombotic thrombocytopenic purpura (TTP) is a microangiopathy resulting from an inherited or acquired severe deficiency in a disintegrin and metalloproteinase called ADAMTS-13. Acquired or immune TTP...

A 49-year-old Man with Ischemic Cardiomyopathy and Persistent Hemoptysis for Eighteen Months.

Mar 14, 2022

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of recurrent episodes of diffuse alveolar hemorrhage (DAH). IPH commonly manifests with hemoptysis, radiologic chest infiltrates and anemia. Th...

Role of platelet to lymphocyte ratio and red cell distribution width in predicting postoperative complications in patients with acute mesenteric ischemia.

Mar 07, 2022

The predictive value of the platelet to lymphocyte ratio (PLR) and red cell distribution width (RDW) have been demonstrated in different types of abdominal surgery. The aim of this study was to invest...

NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions.

Mar 07, 2022

The bioavailability and regulation of iron is essential for central biological functions in mammals. The role of this element in ferroptosis and the dysregulation of its metabolism contribute to disea...

Arbutus Unedo Honey and Propolis Ameliorate Acute Kidney Injury, Acute Liver Injury, and Proteinuria via Hypoglycemic and Antioxidant Activity in Streptozotocin-Treated Rats.

Feb 28, 2022

Honey and propolis have biological and therapeutic effects in various pathological and clinical conditions such as hyperglycemia and diabetes. However, the combined use of honey and propolis has not b...

Exploring crucial molecular events in pearl oyster after pre-grafting conditioning by genome-wide bisulfite sequencing for DNA methylation analysis.

Feb 21, 2022

Pre-grafting condition is an important method to promote recovery from transplant surgery during pearl production. In the present study, we constructed two DNA methylomes from pearl oysters with and w...

Effect of age, cerebral infarcts, vasculopathy and haemoglobin on cognitive function, in Tanzanian children with sickle cell anaemia.

Feb 21, 2022

Developmental difficulties in many cognitive domains are common in children with sickle cell anaemia (SCA). Children with stroke are most affected but delayed or atypical cognitive function has been r...