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Orthopedics

Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma.

Jan 31, 2022

Pivotal clinical trials of B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor (CAR) T-cell therapy in patients with relapsed/refractory multiple myeloma (MM) resulted in remarkable in...

Black Patients More Likely to Have Negative Descriptors in Notes

Jan 25, 2022

MONDAY, Jan. 24, 2022 (HealthDay News) -- Black patients are more likely than White patients to have at least one negative descriptor in the history and physical notes of their electronic health recor...

Chronic low back pain is associated with impaired bed turning ability: Evaluation by a mobility detection system.

Jan 24, 2022

We aimed to assess and compare kinetics and kinematic variables of bed turning ability using a mobility detection system in patients with and without chronic low back pain and to observe the impacts o...

Arthroscopic debridement for infection after fracture fixation (IAFF) of the ankle: A case report.

Jan 24, 2022

Infection after fracture fixation (IAFF) is one of the most challenging issues for the lower-middle class socioeconomic. It is also related to unsatisfactory outcome of the treatment. Arthroscopy usua...

Reduced intensity hematopoietic stem cell transplantation for myelofibrosis in accelerated-phase.

Jan 24, 2022

Accelerated-phase (AP) myelofibrosis, currently defined by circulating blasts 10-19%, usually confers very high risk for progression and poor outcome. The outcome of hematopoietic stem cell transplant...

Prophylactic Antibiotics Not Needed Before Invasive Dental Procedures

Jan 21, 2022

THURSDAY, Jan. 20, 2022 (HealthDay News) -- There is no evidence to support administering antibiotic prophylaxis before invasive dental procedures (IDP) in patients with prosthetic joints, according t...

Prophylactic Antibiotics Not Needed Before Invasive Dental Procedures

Jan 21, 2022

THURSDAY, Jan. 20, 2022 (HealthDay News) -- There is no evidence to support administering antibiotic prophylaxis before invasive dental procedures (IDP) in patients with prosthetic joints, according t...

Same-Day Discharge Increasing for Hip, Knee Arthroplasty

Jan 20, 2022

THURSDAY, Jan. 20, 2022 (HealthDay News) -- Same-day discharge (SDD) is becoming more common for both total hip arthroplasty (THA) and total knee arthroplasty (TKA), according to a study recently publ...

The diagnostic precision of computed tomography for traumatic cervical spine injury: An in vitro biomechanical investigation.

Jan 17, 2022

CT is considered the best method for vertebral fracture detection clinically, but its efficacy in laboratory studies is unknown. Therefore, our objective was to determine the sensitivity, precision, a...

Engagement in leisure activities and depression in older adults in the United States: Longitudinal evidence from the Health and Retirement Study.

Jan 17, 2022

Receptive cultural engagement (e.g. attending theaters and museums) can reduce depression in older adults. However, whether specific participatory leisure activities are associated with lower rates of...

Bone permeability and mechanotransduction: Some current insights into the function of the lacunar-canalicular network.

Jan 17, 2022

Lacunar-canalicular (LC) permeability involves the passage of fluids, nutrients, oxygen, ions, and signalling molecules through bone tissue, facilitating the maintenance of bone vitality and function ...

Hip Fracture Risk Up With Drug Holiday From Risedronate Versus Alendronate

Jan 13, 2022

THURSDAY, Jan. 13, 2022 (HealthDay News) -- Drug holidays after long-term risedronate are associated with a small increase in the risk for hip fracture compared with drug holidays after long-term alen...

Aquatic Exercise Cuts Pain, Disability From Low Back Pain

Jan 12, 2022

WEDNESDAY, Jan. 12, 2022 (HealthDay News) -- Therapeutic aquatic exercise leads to greater pain alleviation in patients with chronic low back pain compared with physical therapy, according to a study ...

Intrathecal Morphine + Oral Gabapentin Aids Pain Management

Jan 11, 2022

TUESDAY, Jan. 11, 2022 (HealthDay News) -- Combining intrathecal morphine (ITM) and oral gabapentin (GABA) improves pain management in teens undergoing spinal fusion for scoliosis, according to a stud...

Factors at Midlife May Predict Health Trajectory in Women

Jan 11, 2022

MONDAY, Jan. 10, 2022 (HealthDay News) -- Factors in women at midlife associated with clinically important declines in physical health and function later in life include body mass index (BMI), educati...

Robot-assisted ventral sacral Tarlov cystectomy; A case report.

Jan 10, 2022

Although asymptomatic Tarlov cysts (TCs) are reported in up to 13% of the population, symptomatic TCs are rare (less than 1%), making the management of the symptomatic cysts controversial. The most co...

Enzymatically functionalized RGD-gelatin scaffolds that recruit host mesenchymal stem cells in vivo and promote bone regeneration.

Jan 10, 2022

Critical-size bone defects are imposing a substantial biomedical burden. Despite being long regarded as a potential approach to mitigate this burden or an alternative to bone grafts, bone tissue engin...

Effects of organic macro and trace minerals in fast and slower growing broiler breeders' diet on offspring growth performance and tibia characteristics.

Jan 10, 2022

This study was designed to evaluate effects of source of macro and trace minerals (inorganic vs. organic) in fast and slower growing broiler breeders' diets on egg and hatchling mineral content and on...

Duloxetine Does Not Alleviate Pain in Chronic Osteoarthritis

Jan 07, 2022

THURSDAY, Jan. 6, 2022 (HealthDay News) -- For patients with chronic osteoarthritis (OA) pain, duloxetine added to usual care has no effect compared with usual care alone, according to a study publish...

Duloxetine Does Not Alleviate Pain in Chronic Osteoarthritis

Jan 07, 2022

THURSDAY, Jan. 6, 2022 (HealthDay News) -- For patients with chronic osteoarthritis (OA) pain, duloxetine added to usual care has no effect compared with usual care alone, according to a study publish...