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Pain General

Characterization of Cortisol Dysregulation in Fibromyalgia and Chronic Fatigue Syndromes: A State-Space Approach.

Mar 10, 2020

Fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS) are complicated medical disorders, with little known etiologies. The purpose of this research is to characterize FMS and CFS by studying ...

Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis.

Mar 09, 2020

To combine meta-analyses of multiple long-term outcomes in children prenatally exposed to methadone or buprenorphine through their mothers' Opioid maintenance therapy (OMT) with a systematic review of...

Pain catastrophizing as a predictor of suicidal ideation in chronic pain patients with an opiate prescription.

Mar 09, 2020

Chronic pain and opioid use are associated with increased risk for suicidal ideation and behaviors (SIB) in cross-sectional studies, particularly among individuals who catastrophize about their pain. ...

Step-Headache: A Distinct Symptom of Migraine.

Mar 09, 2020

 The diagnosis of migraine depends on various characteristics of headache with their associated constitutional symptoms such as nausea, vomiting, photophobia, and phonophobia. Relatively severe int...

Prolonged Migraine Stuttering Aura: Structural, Functional, and Video Neuroimaging Study of an Atypical Migraine Aura. A Case Report.

Mar 09, 2020

Stuttering is a disorder in the rhythm of speech characterized by an involuntary repetition, prolongation, and cessation of sounds. Neurogenic acquired stuttering is a very rare disorder which could r...

PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache?

Mar 09, 2020

Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) may play an important role in primary headaches. Preclinical evidence suggests that PACAP38 modulates trigeminal nociceptive activity ma...

Effect of Repetitive Transcranial Magnetic Stimulation on Pain Management: A Systematic Narrative Review.

Mar 09, 2020

Recently, clinicians have been using repetitive transcranial magnetic stimulation (rTMS) for treating various pain conditions. This systematic narrative review aimed to examine the use and efficacy of...

Validity of Algorithms for Identification of Individuals Suffering from Chronic Noncancer Pain in Administrative Databases: A Systematic Review.

Mar 09, 2020

Secondary analysis of health administrative databases is indispensable to enriching our understanding of health trajectories, health care utilization, and real-world risks and benefits of drugs among ...

Non-celiac gluten sensitivity and chronic refractory low back pain with spondyloarthritis features.

Mar 09, 2020

To propose the hypothesis that non-celiac gluten sensitivity is associated with chronic low-back pain related to spondyloarthritis, and a gluten free diet has a therapeutic benefit in a subgroup of pa...

Methamphetamine and Opioid Cue Database (MOCD): Development and Validation.

Mar 09, 2020

Drug cue reactivity (DCR) is widely used in experimental settings for both assessment and intervention. There is no validated database of pictorial cues available for methamphetamine and opioids.360 i...

The spatio-temporal distribution of naloxone administration events in rural Ohio 2010-16.

Mar 09, 2020

In 2017, Ohio had the second highest rate of drug overdose deaths in the United States. Current opioid related epidemiologic literature has begun to uncover the environmental level influences on the o...

Botulinum neurotoxin injections for muscle-based (dystonia and spasticity) and non-muscle-based (neuropathic pain) pain disorders: a meta-analytic study.

Mar 09, 2020

Apart from the known efficacy of Botulinum Neurotoxin Type A (BoNT/A) in hyperactive striated and smooth muscles, different pain states have become potential targets of toxin effects. This present stu...

Reactive oxygen species play a role in P2X7 receptor-mediated IL-6 production in spinal astrocytes.

Mar 09, 2020

Astrocytes mediate a remarkable variety of cellular functions, including gliotransmitter release. Under pathological conditions, high concentrations of the purinergic receptor agonist adenosine tripho...

Remission in psoriatic arthritis: Definition and predictors.

Mar 09, 2020

To determine the frequency of remission defined by the absence of the various disease manifestations of psoriatic arthritis (PsA) and identify predictors for remission.Patients followed at the PsA cli...

Nerve growth factor promotes ASIC1a expression via the NF-κB pathway and enhances acid-induced chondrocyte apoptosis.

Mar 09, 2020

Nerve growth factor (NGF) is a neurotrophic factor that is thought to have a broad role in the nervous system and tumors, and has recently been described as a mediator of inflammation. It is not clear...

Differential impact of psychological and psychophysical stress on low back pain in mice.

Mar 09, 2020

Low back pain (LBP) is a highly prevalent and disabling condition whose initiating factors are poorly understood. It is known that psychological and physical stress is associated with LBP but the caus...

Alcohol-aggravated episodic pain in humans with SCN11A mutation and ALDH2 polymorphism.

Mar 09, 2020

Mutations in Nav1.9 encoded by SCN11A have been associated with episodic pain, small-fiber neuropathy and congenital insensitivity to pain. In this study, we collected and characterized one Chinese fa...

Parent cognitive, behavioural, and affective factors and their relation to child pain and functioning in pediatric chronic pain: a systematic review and meta-analysis.

Mar 09, 2020

Prior studies have demonstrated that parental cognitive, behavioral and emotional factors are related to child functioning in children and adolescents with chronic pain. This is particularly important...

Non-surgical mouse model of endometriosis-associated pain that responds to clinically active drugs.

Mar 09, 2020

Endometriosis is an estrogen-dependent inflammatory disease that affects approximately 10% of women. Debilitating pelvic or abdominal pain is one of its major clinical features. Current animal models ...

Examining risk behavior and syringe coverage among people who inject drugs accessing a syringe services program: A latent class analysis.

Mar 09, 2020

Injection drug use (IDU) remains a significant public health problem. IDU has been associated closely with the opioid crisis; driving overdose, HIV, and Hepatitis C (HCV) infection nationwide. Syringe...

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