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Pain General

Early postoperative pain after laparoscopic donor nephrectomy predicts 30-day postoperative infectious complications: a pooled analysis of randomized controlled trials.

Mar 02, 2020

Our research group recently published a positive association between early postoperative pain and 30-day postoperative complications in a broad surgical population. To investigate whether heterogeneit...

TRPV1 antagonist BCTC inhibits pH 6.0-induced pain in human skin.

Mar 02, 2020

Tissue acidosis due to ischemia occurs under several pathological conditions, and is thought to contribute to pain in these circumstances. TRPV1, TRPA1 and ASICs are known to be sensitive to acidic pH...

Common transcriptional signatures of neuropathic pain.

Mar 02, 2020

The dorsal root ganglia is a key structure in nociception and chronic pain disorders. Several gene expression studies of dorsal root ganglia in pre-clinical pain models have been performed, but it is ...

In Vivo Testing of a Prototype Intradural Spinal Cord Stimulator in a Porcine Model.

Mar 02, 2020

Chronic midline low back pain is the number one reason for disability in the United States despite the prolific use of medical and surgical interventions. Notwithstanding the widespread use of epidura...

Preliminary Evidence of Pregabalin Misuse among Prescription and/or Illicit Opioid (Mis)users.

Mar 02, 2020

Pregabalin is approved for the management of neuropathic pain, partial-onset seizures, and fibromyalgia. Although it is considered to have low potential for abuse, reports of misuse of pregabalin are ...

Rome IV Functional Gastrointestinal Disorders and Health Impairment in Subjects With Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome.

Mar 02, 2020

Individuals with hypermobility spectrum disorder or hypermobile Ehlers-Danlos Syndrome (HSD/hEDS) are increasingly encountered by gastroenterologists and pose complex clinical challenges. Uncontrolled...

Yoga therapy for fibromyalgia syndrome: A case report.

Mar 02, 2020

Fibromyalgia is a rheumatologic syndrome leading to increased pain sensitivity, sleep disturbance, fatigue, stiffness, and tenderness of joints, muscles, and tendons due to dysregulation of neurophysi...

Pain catastrophizing mediates the negative influence of pain and trait-anxiety on health-related quality of life in fibromyalgia.

Mar 02, 2020

Patients with fibromyalgia syndrome (FMS) usually display a decrease in health-related quality of life (HRQoL). This decrease in HRQoL is related to clinical pain, anxiety, and depression. This cross-...

Screening for acquired latent tuberculosis in rheumatoid arthritis patients on tumor necrosis factor inhibition therapy in Southern California.

Mar 02, 2020

There are no studies assessing the development of latent tuberculosis infection (LTBI) in patients on tumor necrosis factor inhibitors (TNFα-I) in high TB prevalence areas of the USA. Our objective w...

Proteomic serum profile in menstrual-related and post menopause migraine.

Mar 02, 2020

The aim of this pilot study was to analyze the serum proteomic profile of women suffering from menstrual-related migraine (MM group, n = 15) and migraine in post-menopause (PM group, n = 15) in compar...

A case of esophageal cancer complicated with methotrexate-related lymphoproliferative disorder.

Mar 02, 2020

A 69-year-old woman had been undergoing treatment with methotrexate for rheumatoid arthritis for 9 years. Because fever and right hypochondriac pain continued, she visited the nearby hospital. The en...

Development and validation of a nomogram to predict coronary heart disease in patients with rheumatoid arthritis in northern China.

Mar 02, 2020

We developed and validated a nomogram to predict coronary heart disease (CHD) in patients with rheumatoid arthritis (RA) in northern China. We analyzed a cohort of RA patients admitted to the Departme...

Prevent action of magnoflorine with hyaluronic acid gel from cartilage degeneration in anterior cruciate ligament transection induced osteoarthritis.

Mar 02, 2020

According to the Chinese medicine, magnoflorine exerted significant anti-inflammatory effects and potentially promoted synthesis of proteoglycans in chondrocytes to reverse the progression of rheumato...

Brain metabolites in chronic migraine patients with medication overuse headache.

Feb 28, 2020

Medication overuse headache may be associated with widespread alterations along the thalamocortical pathway, a pathway involved in pain perception and disease progression. This study addressed whether...

Acute Dystonic Reactions in Children Treated for Headache With Prochlorperazine or Metoclopramide.

Feb 28, 2020

The incidences of dystonic reactions to metoclopramide and prochlorperazine have not been well characterized in children.Medical record data were reviewed for patients at a tertiary care pediatric hos...

Persistent post-traumatic headache attributed to mild traumatic brain injury: Deep phenotyping and treatment patterns.

Feb 28, 2020

To investigate clinical characteristics and treatment patterns in persistent post-traumatic headache attributed to mild traumatic brain injury.A total of 100 individuals with persistent post-traumatic...

Patient-Reported Outcome in Two Chronic Diseases: A Comparison of Quality of Life and Response Profiles in Severe Migraine and Severe Asthma.

Feb 28, 2020

Migraine and asthma are two frequent, disabling, chronic disorders with a major impact on patient well-being. The objectives of this study were to compare subjective well-being between patients with s...

[Migraine burden and clinical inertia: what can we do?]

Feb 28, 2020

To study the compliance of neurologists and headache specialists to chronic headache and chronic migraine (CM) diagnosis and treatment guidelines.The survey included 634 neurologists from all regions ...

Adherence to ophthalmological screening recommendations and course of uveitis in children with juvenile idiopathic arthritis: data from the Inception Cohort of Newly diagnosed patients with JIA (ICON-JIA) study.

Feb 28, 2020

As JIA-associated uveitis (JIAU) is asymptomatic in the majority of patients, ophthalmologic screening examinations are recommended, depending on the risk constellation for uveitis development. This s...

Almost 1 in 5 South African adults have chronic pain: a prevalence study conducted in a large nationally representative sample.

Feb 28, 2020

Limited information on the prevalence and risk factors for chronic pain is available for developing countries. Therefore, we investigated the prevalence of chronic pain, and the association between th...

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