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Pain General

Ictal-Interictal Comparison of FDG-PET Findings in Sporadic Hemiplegic Migraine.

Feb 04, 2020

Sporadic hemiplegic migraine (SHM) is characterized by a prolonged motor aura that accompanies a migraine attack, and its underlying pathophysiology remains unclear. Functional image during the event ...

Clinical Perspectives on Headache after Traumatic Brain Injury

Feb 04, 2020

Headache after traumatic brain injury (TBI) is frequent and persistent over the first year after injury. Providers may need to focus on different symptoms presentations depending on their patient's TB...

Analysis of the effectiveness of the prophylaxis of vestibular migraine depending on the diagnostic category and the prescribed drug.

Feb 04, 2020

Vestibular migraine (VM) consists of recurrent episodes of vestibular symptoms that are accompanied by migraine in at least 50% of the episodes. The criteria of the Bárány Society include two diagno...

Determination of the increased risk of developing atrial fibrillation in fibromyalgia syndrome.

Feb 04, 2020

Atrial fibrillation (AF) is the leading cause of ischemic stroke and is one of the most common arrhythmias. Previous studies have shown that impaired diastolic functions, P wave dispersion (Pd), and p...

Anxiety Disorders and Medical Comorbidity

Feb 04, 2020

Anxiety disorders are debilitating psychological disorders characterized by a wide range of cognitive and somatic symptoms. Anxiety sufferers have a higher lifetime prevalence of various medical probl...

The role of socioeconomic status in the susceptibility to develop systemic lupus erythematosus in Mexican patients.

Feb 04, 2020

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder for which Major Histocompatibility Complex (MHC) genes are well-identified as risk factors. SLE patients have different phenot...

microRNA-21 Aggravates Lipopolysaccharide-Induced Inflammation in MH7A Cells Through Targeting SNF5.

Feb 04, 2020

The research aims to explore the roles and underlying mechanisms of microRNA-21 (miR-21) in lipopolysaccharide (LPS)-induced inflammation in MH7A cells. Cells were treated with LPS and/or transfected ...

Autoantibodies against P29ING4 are associated with complex regional pain syndrome.

Feb 04, 2020

Complex regional pain syndrome (CRPS) is a complication following trauma or surgery and may be difficult to diagnose since biomarkers are lacking. Using protein array technology, we found antibodies b...

Characteristics and Symptom Severity of Patients Reporting Systemic Lupus Erythematosus in the PatientsLikeMe Online Health Community: A Retrospective Observational Study.

Feb 04, 2020

Online health communities and research networks such as PatientsLikeMe (PLM) capture patient perspectives of diseases, including systemic lupus erythematosus (SLE). We performed a retrospective observ...

Experience of musculoskeletal ultrasound scanning improves physicians' physical examination skills in assessment of synovitis.

Feb 04, 2020

Musculoskeletal ultrasound (US) is more sensitive than physical examination in detecting synovitis and helps physicians to understand its pathophysiology. In this study, we aimed to determine if the e...

Proactive Pain Management May Cut Postop Opioid Prescriptions

Feb 03, 2020

MONDAY, Feb. 3, 2020 (HealthDay News) -- An enhanced recovery after surgery program complemented by a preemptive pain management program is associated with a decrease in opioid prescriptions at discha...

The Chronic Migraine Brain: What Have We Learned From Neuroimaging?

Jan 31, 2020

Chronic migraine is a highly disabling disease with a great impact on socioeconomic functioning and quality of life of migraine patients. Chronic migraine usually evolves from episodic migraine that g...

Prevalence of visual snow syndrome in the UK.

Jan 31, 2020

Visual snow syndrome is a recently described condition of unknown prevalence. We investigated the prevalence in a representative population sample from the UK and tested the hypothesis that visual sno...

Machine Learning Increases Diagnosticity in Psychometric Evaluation of Alexithymia in Fibromyalgia.

Jan 31, 2020

Here, we report an investigation on the accuracy of the Toronto Alexithymia Scale, a measure to assess alexithymia, a multidimensional construct often associate to fibromyalgia. Two groups of particip...

Is background methotrexate advantageous in extending TNF inhibitor drug survival in elderly patients with rheumatoid arthritis? An analysis of the British Society for Rheumatology Biologics Register.

Jan 31, 2020

To evaluate drug survival with monotherapy compared with combination therapy with MTX in RA older adults.Patients from the British Society for Rheumatology Biologics Register, a prospective observatio...

Validated LC-MS/MS method for quantitation of a selective JAK1 inhibitor, filgotinib in rat plasma and its application to a pharmacokinetic study in rats.

Jan 31, 2020

Filgotinib is a selective JAK1 (Janus kinase) inhibitor, filed in Japan for the treatment of rheumatoid arthritis. In this paper we are reporting a validated LC-MS/MS (liquid chromatography coupled wi...

Age of onset as an influencing factor for disease severity in children with familial Mediterranean fever.

Jan 31, 2020

To define the demographic, clinical and genetic features of familial Mediterranean fever (FMF) patients with early disease onset and to compare them with late-onset FMF patients. Patients were divide...

Conventional versus ultrasound treat to target: no difference in magnetic resonance imaging inflammation or joint damage over 2 years in early rheumatoid arthritis.

Jan 31, 2020

To investigate whether an ultrasound-guided treat-to-target strategy for early RA would lead to reduced MRI inflammation or less structural damage progression compared with a conventional treat-to-tar...

MyD88-dependent influx of monocytes and neutrophils impairs lymph node B cell responses to chikungunya virus infection via Irf5, Nos2 and Nox2.

Jan 31, 2020

Humoral immune responses initiate in the lymph node draining the site of viral infection (dLN). Some viruses subvert LN B cell activation; however, our knowledge of viral hindrance of B cell responses...

Association between MRI findings and patient-reported outcomes in patients with rheumatoid arthritis in clinical remission and at relapse.

Jan 30, 2020

To investigate whether magnetic resonance imaging (MRI) pathologies in the wrist/hand of rheumatoid arthritis (RA) patients are associated with patient-reported outcomes (PROs) at clinical remission a...

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