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Pain General

Individual dimensions of pain catastrophizing do not mediate the effect of sociodemographic and psychological factors on chronic orofacial pain severity, interference, and jaw limitation: A structural equation modeling approach.

May 01, 2023

Pain catastrophization (PC), involving rumination, magnification, and helplessness, can be viewed as a coping strategy associated with chronic pain. PC is considered a driving force in mediating pain-...

An unusual manifestation in a pediatric patient with MAFB mutation: Sacroiliitis in multicentric carpotarsal osteolysis syndrome.

Apr 24, 2023

Multicentric carpotarsal osteolysis (MCTO) syndrome, is typically characterized by progressive bone resorption in especially carpal and tarsal bones, in addition to abnormal facial appearance and prot...

Long-term Efficacy of Pectoserratus Plane Block for Prevention of Post-mastectomy Pain Syndrome: Extended Follow-up From a Randomised Controlled Trial.

Apr 24, 2023

Pectoserratus plane block (PSPB) leads to lower postoperative pain intensity. We examined whether PSPB could also reduce the incidence of post-mastectomy pain syndrome (PMPS) in women undergoing breas...

Consciousness, Exascale Computational Power, Probabilistic Outcomes, and Energetic Efficiency.

Apr 17, 2023

A central problem in the cognitive sciences is identifying the link between consciousness and neural computation. The key features of consciousness-including the emergence of representative informatio...

Get your head in the game: a replicated single-case-experimental-design evaluating the effect of a novel virtual reality intervention in people with chronic low back pain.

Apr 10, 2023

Chronic low back pain (CLBP) is a leading cause of disability worldwide. Contemporary treatment of CLBP is suboptimal, with small/moderate effect sizes and high relapse rates. Virtual reality (VR) is ...

Pain-Related Anxiety in Spanish-Speaking Mexican Americans who Report Chronic Pain: Psychometric Evaluation of a New Spanish Adaptation of the 20-Item Pain Anxiety Symptom Scale (PASS-20).

Apr 10, 2023

The 20-item Pain Anxiety Symptom Scale (PASS-20) was adapted for Spanish-speaking Mexican Americans who report chronic pain (SSMACP). The instrument measures pain-related anxiety with fear, physiologi...

Cannabinoid receptors involved in descending inhibition on spinal seizure-like activity in the phrenic output.

Apr 03, 2023

Seizure-like burst activities are induced by blockade of GABAA and/or glycine receptors in various spinal ventral roots of brainstem-spinal cord preparation from neonatal rodents. We found that this i...

Local Anesthesia Versus General Anesthesia in Percutaneous Interlaminar Endoscopic Discectomy: A Meta-analysis.

Apr 03, 2023

To systematically evaluate the safety and efficacy of Local anesthesia (LA) and general anesthesia (GA) in percutaneous interlaminar endoscopic discectomy (PIED).We searched the MEDLINE, EMBASE, Europ...

Effect Of A Behavioural Therapy-Based Virtual Reality Application On Quality Of Life In Chronic Low Back Pain.

Apr 03, 2023

Low back pain is the leading cause of years lived with disability with a large impact on quality of life and resistant to a broad array of current treatments. This study aims to investigate the effect...

Changes in Brain GABA and Glutamate and Improvements in Physical Functioning Following Intensive Pain Rehabilitation in Youth With Chronic Pain.

Mar 27, 2023

Intensive interdisciplinary pain treatments (IIPT) have been developed to treat youth with unmanaged chronic pain and functional disability. Dysregulation of metabolites gamma-aminobutyric acid (GABA...

DEPRESSION, COGNITION, AND PAIN: EXPLORING INDIVIDUAL, CULTURAL AND COUNTRY-LEVEL EFFECTS ACROSS EUROPE.

Mar 27, 2023

The aim of this paper was to investigate the role of economic (e.g. GDP per capita), political (e.g. healthcare spending), cultural (country-level aggregates norms) and individual correlates (e.g., de...

P2X7-NLRP3-Caspase-1 signaling mediates activity-induced muscle pain in male but not female mice.

Mar 20, 2023

We developed an animal model of activity-induced muscle pain that is dependent on local macrophage activation and release of interleukin-1β (IL-1β). Activation of purinergic type 2X (P2X) 7 receptor...

Barriers and facilitators of evidence-based psychotherapies for chronic pain in adults: A systematic review.

Mar 20, 2023

Cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and mindfulness-based stress reduction (MBSR) have demonstrated effectiveness for improving outcomes in chronic pain. These...

[First Experience with Diaphragm Pacing System in the Czech Republic].

Mar 13, 2023

Patients with impaired diaphragm function are dependent on long-term mechanical ventilation. It is associated with numerous health complications as well as significant economic burden. Intramuscular d...

The utility of intraoperative neuromonitoring in pediatric surgical oncology.

Mar 13, 2023

Intraoperative nerve monitoring (IONM) is a technique used to decrease the possibility of nerve-associated morbidity and damage to nearby neural structures during complex surgical procedures. The use ...

Peripheral transient receptor potential vanilloid type 4 hypersensitivity contributes to chronic sickle cell disease pain.

Mar 13, 2023

Debilitating pain affects the lives of patients with sickle cell disease (SCD). Current pain treatment for patients with SCD fail to completely resolve acute or chronic SCD pain. Previous research ind...

CpG methylation levels in HPA axis genes predict chronic pain outcomes following trauma exposure.

Mar 13, 2023

Chronic posttraumatic musculoskeletal pain (CPTP) is a common outcome of traumatic stress exposure. Biological factors that influence the development of CPTP are poorly understood, though current evid...

Evaluating the impact of metabolic surgery on patients with prior opioid use.

Mar 06, 2023

Metabolic surgery is the most effective treatment for obesity and may improve obesity-related pain syndromes. However, the effect of surgery on the persistent use of opioids in patients with a history...

"Like it was just everyday business": A qualitative study of pharmacy-based naloxone and syringe customer experience.

Mar 06, 2023

As rates of overdoses involving opioids continue to rise in the United States, community pharmacies are uniquely positioned as a central access point of care for individuals to access harm reduction s...

A cross-sectional study on the personality traits of episodic and chronic migraine patients.

Mar 06, 2023

Migraine, is a common neurological disorder that may be associated with certain personality traits. This study aims to identify and compare the personality traits accompanying the clinical and sociode...

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