The purpose of this quality improvement initiative was to demonstrate the value of having a clinical pain pharmacist in transitional perioperative pain management. Patients were referred to ...
There are significant medical risks of long-term opioid therapy (LTOT) for chronic pain. Consequently, there is a need to identify effective interventions for the reduction of high-dose full...
Alcohol screening may be associated with health outcomes that cluster with alcohol use (ie, alcohol-clustering conditions), including depression, anxiety, and use of tobacco, marijuana, and ...
As the opioid crisis worsens across the United States, the factors that impact physician training in management of substance use disorders become more relevant. A thorough understanding of t...
Opioid receptors (ORs) are among the best studied G protein-coupled receptors due to their involvement in neurological disorders and important role in pain treatment. Contrary to the classic...
To combine meta-analyses of multiple long-term outcomes in children prenatally exposed to methadone or buprenorphine through their mothers' Opioid maintenance therapy (OMT) with a systematic...
Chronic pain and opioid use are associated with increased risk for suicidal ideation and behaviors (SIB) in cross-sectional studies, particularly among individuals who catastrophize about th...
: Due to the increased use of opioids for pain and their abuse globally, the rate of restrictive side effects is elevating. Opioid-induced constipation (OIC) is probably the most widespread,...
The question over whether to administer clinically assisted nutrition and hydration (CANH) to a dying patient is controversial, with much debate concerning this sensitive issue. The administ...
Despite significant research progress on the pathogenesis, molecular biology, diagnosis, treatment, and prevention of cancer its morbidity and mortality is still high around the world. The e...
Social media data are being increasingly used for population-level health research because it provides near real-time access to large volumes of consumer-generated data. Recently, a number o...
The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are also ineffective against neuropathic pain. Recent reports have suggested that inhibitors of th...
Opioid agonist activation at the mu opioid receptor (MOR) can lead to a wide variety of physiological responses. Many opioid agonists share the ability to selectively and preferentially acti...
Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the development of tolerance and of opioid-induced hyperalgesia, both limiting the analgesic use of morp...
In the past decade, there has been a rising trend in the emergency department (ED) visits in the US and these visits carry a significant burden of prescription opioids. This study utilized t...
While the frequency of short-term side effects of opioids are well-known, the long-term risks of opioid use are inadequately quantified. For a study published in Annals of Emergency Medicine...
Program linked to opioid-free discharge following elective minimally invasive benign foregut surgery...
Current estimates suggest that 70-90% of opioids prescribed after surgery go unused, with most patients not disposing these medications that can become a common source of misuse and abuse, e...
Significantly more patients treated with Ubrelvy versus placebo achieved pain freedom two hours post-treatment TUESDAY, Dec. 24, 2019 (HealthDay News) -- Ubrelvy (ubrogepant) tablets ha...
Percentage of critical care admissions and suicidal intent increased in each era. MONDAY, Dec. 30, 2019 (HealthDay News) -- The severity of pediatric admissions for acute opioid ingestion...
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