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Flu

Homogenization of a Reaction Diffusion Equation can Explain Influenza A Virus Load Data.

Jun 24, 2021

We study the influence of spatial heterogeneity on the antiviral activity of mouse embryonic fibroblasts (MEF) infected with influenza A. MEF of type Ube1Lare composed of two distinct sub-populations,...

Carrageenan nasal spray may double the rate of recovery from coronavirus and influenza virus infections: Re-analysis of randomized trial data.

Jun 17, 2021

In this individual patient data meta-analysis we examined datasets of two randomized placebo-controlled trials which investigated the effect of nasal carrageenan separately on children and adults. In ...

Natural killer cells in antiviral immunity.

Jun 14, 2021

Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we review recent insights into the role of NK cells in viral infections, with particular emphasis...

Does Covid-19 in Children Have a Milder Course than Influenza?

Jun 10, 2021

In December 2019, a novel type of coronavirus infection emerged in the Wuhan province of China and began to spread rapidly. In this study, we aimed to determine the differences between COVID-19 diseas...

Mammalian cells use the autophagy process to restrict avian influenza virus replication.

Jun 10, 2021

Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing avian PB2 in...

Development and validation of the treatmentself-regulation questionnaire assessing healthcare professionals' motivation for flu vaccination (TSRQ-Flu).

Jun 03, 2021

We use self-determination theory to extend the conceptual understanding of flu vaccine hesitancy among health professionals. The scale sheds light on the role played by motivational factors above and ...

The Psychological Impact of Hypertension During COVID-19 Restrictions: Retrospective Case-Control Study.

Jun 03, 2021

It is unclear how people with hypertension are responding to the COVID-19 pandemic given their increased risk, and whether targeted public health strategies are needed.This retrospective case-control ...

Anisodamine (654-2) inhibits inflammation to alleviate influenza A virus-induced acute lung injury.

Jun 03, 2021

Acute lung injury (ALI) is one of the leading causes of acute respiratory failure (ARF) and respiratory virus caused death. This study aimed to elucidate the potential effect of Anisodamine (ANI 654-2...

Sleep Disorders in Children: A Rapidly Evolving Field Seeking Consensus.

May 24, 2021

Narcolepsy is a life-long sleep disorders with two distinct subtypes, narcolepsy type I and narcolepsy type II. It is now well recognized that the loss of hypocretin neurons underlies pathogenesis of ...

The changing influenza activity in the Southern hemisphere countries during the COVID-19 pandemic.

May 24, 2021

While the reduction in influenza cases in the Northern hemisphere during 2020 has been widely reported, the Southern hemisphere's influenza transmission dynamics remain uncharacterized.We analyzed the...

Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses.

May 17, 2021

Inflammatory diseases are frequently treated with Janus kinase (JAK) inhibitors to diminish cytokine signaling. These treatments can lead to inadvertent immune suppression and may increase the risk of...

[Care of rheumatology patients during the lockdown in early 2020 : Telemedicine, delegation, patient satisfaction and vaccination behavior].

May 13, 2021

Telemedicine was implemented in outpatient care during the lockdown between March and May 2020. The aim of the study was to assess patients from a private practice and the university outpatient depart...

Allergy to COVID-19 vaccines: A current update.

May 10, 2021

Adverse allergic reactions due to the administration of the vaccines developed for the protection of coronavirus disease 2019 (COVID-19) have been reported since the initiation of the vaccination camp...

Adult preventive vaccines with other synergistic lifestyle options: is it time to add these ancillary benefits to the overall AS management checklist?

May 10, 2021

To review the potential ancillary cardiovascular and other health impacts of compliance with general adult vaccination series in the prostate cancer active surveillance (AS) population. No previous re...

Epidemiology and factors associated with the severity of viral acute lower respiratory infection in children hospitalized in Manaus, Amazonas, in 2017-2018: An observational study.

May 06, 2021

To investigate the epidemiology and factors associated with the severity of viral acute lower respiratory infection (ALRI) in children hospitalized in Manaus, Amazonas, in 2017 to 2018.Retrospective c...

Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection.

May 06, 2021

Tissue macrophages self-renew during homeostasis and produce inflammatory mediators upon microbial infection. We examined the relationship between proliferative and inflammatory properties of tissue m...

The Ferret as a Model for Filovirus Pathogenesis and Countermeasure Evaluation.

May 06, 2021

The domestic ferret (Mustela putorius furo) has long been a popular animal model for evaluating viral pathogenesis and transmission as well as the efficacy of candidate countermeasures. Without questi...

SARS-CoV-2 Worldwide Replication Drives Rapid Rise and Selection of Mutations across the Viral Genome: A Time-Course Study - Potential Challenge for Vaccines and Therapies.

May 03, 2021

Scientists and the public were alarmed at the first large viral variant of SARS-CoV2 reported in December 2020. We have followed the time course of emerging viral mutants and variants during the SARS-...

Seasonal variations in blood culture numbers and time to positivity and potential impact of reducing incubation periods.

Apr 26, 2021

Patients with viral respiratory infections often present symptoms compatible with bloodstream infections. Consequently, the winter period commonly associated with epidemic respiratory illnesses shows ...

Seroprevalence of influenza A (H9N2) virus infection among humans in China: A meta-analysis.

Apr 19, 2021

Herein, we conducted a meta-analysis aimed at comprehensively assessing avian influenza A (H9N2) virus infection seroprevalence and infection-related risk factors among humans in China. We reviewed pu...