In this individual patient data meta-analysis we examined datasets of two randomized placebo-controlled trials which investigated the effect of nasal carrageenan separately on children and adults. In both trials,...
Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we review recent insights into the role of NK cells in viral infections, with particular emphasis on human studies. We first...
In December 2019, a novel type of coronavirus infection emerged in the Wuhan province of China and began to spread rapidly. In this study, we aimed to determine the differences between COVID-19 disease and Influenza.This...
Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing avian PB2 infects mammalian cells, viral...
We use self-determination theory to extend the conceptual understanding of flu vaccine hesitancy among health professionals. The scale sheds light on the role played by motivational factors above and beyond traditional cognitive...
It is unclear how people with hypertension are responding to the COVID-19 pandemic given their increased risk, and whether targeted public health strategies are needed.This retrospective case-control study compared people with...
Acute lung injury (ALI) is one of the leading causes of acute respiratory failure (ARF) and respiratory virus caused death. This study aimed to elucidate the potential effect of Anisodamine (ANI 654-2) on influenza A virus...
Narcolepsy is a life-long sleep disorders with two distinct subtypes, narcolepsy type I and narcolepsy type II. It is now well recognized that the loss of hypocretin neurons underlies pathogenesis of narcolepsy type I, however,...
While the reduction in influenza cases in the Northern hemisphere during 2020 has been widely reported, the Southern hemisphere’s influenza transmission dynamics remain uncharacterized.We analyzed the change in the...
Inflammatory diseases are frequently treated with Janus kinase (JAK) inhibitors to diminish cytokine signaling. These treatments can lead to inadvertent immune suppression and may increase the risk of viral infection. Tyrosine...
Telemedicine was implemented in outpatient care during the lockdown between March and May 2020. The aim of the study was to assess patients from a private practice and the university outpatient department with respect to patient...
Adverse allergic reactions due to the administration of the vaccines developed for the protection of coronavirus disease 2019 (COVID-19) have been reported since the initiation of the vaccination campaigns. Current analyses...
